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Cobese (Orlistat)

Cobese is a reversible active-site inhibitor of gastrointestinal lipases. Cobese forms a covalent bond with the active serine site in gastric and pancreatic lipases, thereby inhibiting their activity and preventing dietary fat from being hydrolyzed and absorbed.

Other names for this medication:
Orlistat, Cobese, Ishape, Lipocut, Lipophage, Obelit, Obezita, Oristal, Orlica, Reeshape, Vyfat, Xenical,

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This medication is used along with a doctor-approved reduced-calorie diet, exercise, and behavior modification program to help significantly overweight (obese) persons lose weight. Taking Cobese can also help prevent you from regaining the weight you have lost. Losing weight and keeping it off can reduce the many health risks that obesity causes, including heart disease, diabetes, high blood pressure, some forms of cancer, certain breathing problems, and a shorter life span. Dietary fats need to be broken down into smaller pieces before the body can absorb them. Cobese works by blocking the enzyme that breaks down fats in your diet. This undigested fat then passes out of your body in your bowel movement. Cobese does not block the absorption of calories from sugar and other non-fat foods, so you still need to restrict your total intake of calories.

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It showed that the participants, who were not aware they were executing familiar sequences in a somewhat different task, had no benefits of prior practice. Analysis of epidemiological as well as survival differences among the multiethnic population of Malaysia with prostate cancer is important. Kallistatin is a serpin first identified as a specific inhibitor of tissue kallikrein. In addition, we aimed to create correlated factor models to describe the support activities in order to identify ways to promote these activities among occupational health nurses. However, recent studies have been restricted to the circulatory disorder and could not suggest the pathologic core to explain all of the characteristics of BSS.

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Although prior studies have suggested a role of cardiometabolic health on pathogenesis of amyotrophic lateral sclerosis (ALS), the association with diabetes mellitus has not been widely examined. Synthesis of a new chiral bisphospholane ligand for the Rh(I)-catalyzed enantioselective hydrogenation of isomeric beta-acylamido acrylates. In mild to moderate stroke patients, the MRS seems to detect small and significant treatment effect changes as compared to the BI. Raising the water temperature from 20 to 24 degrees C alleviated the hypothermia, but did not remove the significant drop in core temperature when using 30-s inter-trial interval. BH3-only proteins constitute a family of apoptosis inducers that mediate proapoptotic signals.

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Interaction of sialosyl cholesterol with the cell surface of rat astrocytes and its biological activities. In addition, we show that a distinct region in Bub1 mediates kinetochore localization of BubR1 through direct binding, but surprisingly removal of this region increases checkpoint strength. The paper presents the main features of the module and provides some examples illustrating the capability of the model in environmentally assessing and discriminating the environmental performance of alternative biological treatment technologies in relation to their mass flows, energy consumption, gaseous emissions, biogas recovery and compost/digestate utilization. The suborder Anthropoidea of the primates has traditionally been divided in three superfamilies: the Hominoidea (apes and humans) and the Cercopithecoidea (Old World monkeys), together comprising the infraorder Catarrhini, and the Ceboidea (New World monkeys) belonging to the infraorder Platyrrhini.

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The activity toward natural lysosomal protein acceptors was absent or deficient in cell preparations from all patients with classical as well as variant forms of mucolipidoses II and III. Second, we examined the effect of isolation on plant reproduction by monitoring fruit and seed production, as well as pollinator activity and assemblage, in small flower arrays transplanted in hedgerows at increasing distances from forest and from each other. (2) EGb and Que were able to enhance the SOD activity and reduce the production of MDA. Alternative oxidase (AOX) is a mitochondrial terminal oxidase that uncouples the consumption of reducing power from ATP synthesis. The parameter set of the GMM was sequentially estimated based on maximum likelihood, subject to constraints derived from the relationship between EMG burst and non-burst distributions.

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Development of hematological and immunological characteristics in neonatal rats. The acoustic hood: a patient-independent device improving acoustic noise protection during neonatal magnetic resonance imaging. vulpes appeared among red foxes (Vulpes vulpes) in Scandinavia (south-west Finland) for the first time in this century in 1967. Morphogenesis and larval morphology were studied in the guinea pig and described herein. Polymerase chain reaction (PCR) analysis of bone marrow at the time of diagnosis was positive for both BCL-2/JH and CDRIII rearrangements.

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An understanding of the mechanisms by which DNA polymerases avoid or generate various mutations depends on the definition of the parameters that influence the frequency and specificity of particular errors. The effect of human skin temperature on electrocutaneous sensitivity was examined using brief capacitive discharges.

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Optimization of attenuation estimation in reflection for in vivo human dermis characterization at 20 MHz. If this is not so, one often has an inadvertent category I flow (flows with specified exit pressure) without the explicit knowledge of the exit pressure value. Because of macrocrania, hypertelorism and epidermal punctiform lesions in the palm of the hand, Gorlin syndrome was clinically suspected and molecularly confirmed by finding a deletion of 22 base pairs in the PTCH1 gene. Thus, it is essential to consider the role of cell loss in the tumorigenic process. The fusion proteins were used to identify cellular proteins that bind to pVHL in vitro.

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Plasmodium-infected mosquitoes were only found in the forest and on the way to the forest. There may be associated hypotension, bradycardia, hyponatremia, hypothermia, inappropriate antidiuretic hormone secretion, and difficulty in micturition. The highest level of biotinylation is characterized by the formation of a biotinylated nucleic acid-avidin complex with no electrophoretical mobility.

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An update on family medicine participation in Clinical and Translational Science Awards (CTSAs). Patients had significantly lower concentrations of the three elements Se, Zn, and Mn. Following a 7-day interval after discontinuing the MAP treatment, a challenge dose (0.5 mg/kg) of apomorphine was administered. This process also explains the very rapid rate of myopia progression of lid sutured eyes. According to the location of their parathyroid autograft, patients were divided into an Intramuscular group and a Subcutaneous group.

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Robustness of the tuning of fly visual interneurons to rotatory optic flow. Planned accrual was 25, but the study was closed prematurely because of slow accrual. There has been conflicting evidence on the use of living donor liver transplantation (LDLT) in patients with high MELD scores. Use of antipsychotics in the treatment of major depressive disorder in the U.S.

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The tuberous root of sweet potato is an important agricultural and biological organ. We used a range of methods to examine stages of the life cycle in culture and in frog skin, and to assess ultrastructural pathology in the skin of 2 frogs. Chronic treatment with BR-16A (20-500 mg/kg) followed by saline on days 1 to 9 failed to produce any significant change in tail-flick latency from the saline-pretreated group in mice.

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Modulation of the 5-nitro-furan-2-carboxylic moiety resulted in a drastic decrease in inhibitory potency. Production and emission of phosphine gas from wetland ecosystems. By integrating the functions of the managed care cycle and the revenue cycle, providers can more readily obtain appropriate payment.

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The results of this study suggest that the psychiatric syndromes present in MCI might be related to MCI per se. Chemometric analysis confirmed the classification of water purity of the Brda river made by the Inspection of Environmental Protection but the results showed more differentiation between monitored locations. (Cytometry 6:620-626, 1985) for the calculation of the DNA synthesis time, TS using flow cytometry to monitor the progression of cells that have been pulse-labeled by bromodeoxyuridine (BrdUrd).

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Careful clinical examination should lead to the recognition of more of these lesions, which are easily confused with warts and calluses. Using Poisson regression models, we assessed the relative risk of dying from ovarian cancer in zones around installations, and analyzed the effect of industrial groups and pollutant substances. Light and electron microscopical visualization of selenium in adrenal glands from rats exposed to sodium selenite. This review provides a background to the IMP protein family with an emphasis on human IMP2, followed by a closer look at the GWA studies to evaluate the significance, if any, of the proposed correlation between IMP2 and T2D.

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Furthermore, our observations modify the view that axon caliber is dependent on normal myelin. Lamina propria DC were recently shown to gain direct access to the intestinal lumen by virtue of epithelium-penetrating dendrites. At 50 and 30 microg/mL lupeol showed a marked inhibitory activity on HUVEC tube formation while it did not affect the growth of tumor cell lines such as SK-MEL-2, A549, and B16-F10 melanoma.

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There were no statistically significant differences between USG and FG. With the dizzying changes in the rapidly evolving profession of radiology, the structure of resident education in the associated sciences of imaging, physics, radiobiology, and radiation effects must be reevaluated continually. These isolates resulted in smaller population reductions than did E. Using the Taiwan National Health Insurance Research Database we conducted a population-based cohort study. The duration of treatment was significantly lower in patients treated with cidofovir until eradication of JRRP compared to patients treated with surgery only.

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Indeterminacy in plants is a characteristic of shoot and root meristems, which must balance maintenance of indeterminacy with organogenesis. Here we used mutational analysis and protein microsequencing to demonstrate that a caspase target site, located in the linker region between the Rel and the IkappaB-like domain, is the site of signal-dependent cleavage.

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Red clover (RC)-derived dietary isoflavones have been implicated as potential preventative agents for the development and prevalence of non-malignant prostate diseases. Mating-induced inhibition of receptivity in the female golden hamster. A combination of acute swelling in the operated region and falling haemoglobin post surgery should alert the clinician to possible vascular injury. Acquired retinochoroiditis in hamsters inoculated with ME 49 strain Toxoplasma. Signaling via the fibroblast growth factor receptor 1 (FGFR1, flg) was analyzed in Ba/F3 hematopoietic cells expressing either wild-type or a mutant FGF receptor (Y766F) unable to activate phospholipase C-gamma (PLC-gamma) and stimulate phosphatidylinositol (PI) hydrolysis.

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We examined the results of 55 meta-analyses (579 study comparisons) of genetic associations and tested whether the magnitude of the genetic effect differs in large versus smaller studies. We identify a number of important practices associated with greater PAE, including high-level leadership commitment, goal-setting supported by adequate resources, extensive provider training, use of interdisciplinary care teams, and frequent monitoring and reporting on progress. The altered expression of AR in MAA-treated animals was also seen in seminiferous tubules harvested by laser capture microdissection. In pitching arms, this band is thicker, is more likely to have hypoechoic foci and/or calcifications, and demonstrates more laxity with valgus stress.

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Repeat III has a different conformation at this site and no calcium bound. Resolution of paraneoplastic immune thrombocytopenia following everolimus treatment for metastatic renal cell carcinoma.

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These studies are most appropriate for the sample numbers necessary to identify both common and rare single nucleotide variants, as well as small insertion or deletion events, which may cause complex inherited diseases. The evaluation framework comprised three main components each with specific criteria. Changes induced by diethylstilbestrol implants or cholesterol feeding. The differences between the photoproduct and the deoxy preparation persist to 77 K, the highest temperature studied, and are independent of whether samples are frozen in phosphate buffer or a 50:50 ethylene glycol/phosphate buffer mixture. Personal Belief Exemptions to Vaccination in California: A Spatial Analysis.

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Oviduct sections were divided into isthmus, ampullary, and infundibular regions. Seasonal panic disorder: a possible variant of seasonal affective disorder. Thus, modulation of angiotensin II-stimulated aldosterone secretion produced in vivo by changes in plasma osmolality result, in part, from a direct effect on the glomerulosa cells. There are well-defined methods of interpreting the BBT graph retrospectively that identify a presumptive day of ovulation.

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The factor map of the features of hypnotic states formation is obtained and some variants of the course of hypnotic states are determined in light of domination of the certain factors. Mandibular growth in subjects with infraoccluded deciduous molars: a superimposition study.

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Risedronate prevented GC-induced trabecular bone loss by preventing GC-induced increase in bone erosion although it also suppressed bone formation (mineralizing surface, mineral apposition rate, and bone formation rate). Activity of glucose-6-phosphate dehydrogenase and acid phosphatase in nonkeratinized and keratinized oral epithelium and epidermis in the rabbit. Exposure to sartans during the last period of gestation seems to be associated with high risk of congenital malformations.

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Furthermore, oxime-induced reactivation is too slow to accomplish a pseudo catalytic function, so that administered BChE may be merely effective as a stoichiometric scavenger. Thus, oral administration of ciprofloxacin is an attractive, cost-effective and safe alternative to prophylaxis in vascular patients capable of taking oral medication on the day of surgery.

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Trismus was caused by the presence of multiple small nests of undifferentiated tumor cells between muscle fibers of the masseter muscles as well as of other skeletal muscles. During the proliferation period, the cells expressed the stem cell markers nestin, ABCG2, SCF, Thy-1 as well as the pancreatic endocrine transcription factor Isl-1.

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Assessment procedures regarding end-of-life decisions in neonatology in the Netherlands. This paper addresses the questions of whether depression compromises cognition in the elderly and whether discernable patterns of cognitive performances could be differentiated between patients with severe depression and those with organic dementia. In this paper, we propose to model the edge information contained in natural scenes as points in the 3D space of positions and orientations. It remains to be seen whether adaptive changes in 5-HT(2C) receptor function represent a common mechanism of clinical antidepressant efficacy. In the longer term it may be possible to use metal-accumulating species to predict toxicity to metal-sensitive species with appropriate field validation.

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Specifically, PS3, which combines age at interview, sex, and smoking status, resulted in the greatest number of significant markers identified. Impact of multiple transarterial chemoembolization treatments on hepatocellular carcinoma for patients awaiting liver transplantation. These changes may place them at risk for morbidity and mortality from diseases fostered by excessive inflammation. Electrochemistry-mass spectrometry for mechanistic studies and simulation of oxidation processes in the environment.

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Identification of host attractants for the ethiopian fruit fly, Dacus ciliatus loew. Nine patients were entered into the phase I and 50 patients were entered into the phase II study. We demonstrated that the cardiac Hsp70 stimulated a 2-fold increase in calcineurin (CaN) activity. Heritability and repeatability of Hereford show-ring placing and associated correlations with individual performance measurements and expected progeny differences. Japanese men with glucose intolerance frequently have small LDL, and this abnormality is associated with other dyslipoproteinemias and increased waist-to-hip ratio.

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Lower values of shear force were observed in the FG line, where a higher level of calpain expression was shown. No differences in measured antibody responses were found with the two types of antigen preparation. Among them, some cases were associated with squamous differentiation. Detection of Myxobolus rotundus (Myxozoa: Myxosporea) in skin mucus of crucian carp Carassius auratus auratus using a monoclonal antibody.

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Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. Although there is little doubt about the efficacy of cardioplegia in the adult heart, there are few studies on the pediatric heart and their results are contradictory. The first element was identified as an insertion in the gene encoding nitrate reductase.

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Inverse relationship between megakaryocyte buoyant density and maturity. Electrophysiologic, antiarrhythmic and cardiovascular actions of UM301, a quaternary ammonium compound. The morphology, and particle size were studied to evaluate the preparation. We found that many labeled neurons showed transition from tangential to radial migration in the region that will develop into the nucleus.

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Although both strains of mice developed the same classes of antibody, C3H/HeN mice had much greater anti-M. Planar bone scan was performed, which showed a lesion in L3 vertebra and was further evaluated with SPECT (Single photon emission computed tomography) study to characterize the lesion. There is limited information about psychosocial and service needs of this group. Among those, arrhythmia, missing beats, pauses, noise, and drifts superimposed on the original ECG traces.

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With these dosing parameters, hind paw placing and stepping reflexes were unaltered, and there were no changes in thermal escape latencies. We found little association between potential exposure and health, after adjustment for demographic variables, and conclude that potential exposure to sarin or cyclosarin at Khamisiyah does not seem to have adversely affected self-perceived health status, as evidenced by a wide range of health measures. The trend in biological monitoring today is to develop tests that provide information on the amount of chemical bound to the critical sites of action (target dose). Our studies identify a novel role for REST in NC cell differentiation and suggest cross talk between cAMP and Wnt signaling in NC lineage specification.

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cobese dosage of aspirin 2015-11-28

Expression of the Chemokine Receptors CXCR3, CXCR4, CXCR7 and Their Ligands in Rhabdomyosarcoma. The integrity of the human genome is preserved by signal transduction pathways called checkpoints, which delay progression through the cell cycle when DNA damage is present. The glycocalyx of the human umbilical vein endothelial cell: an impressive aplenzin patient reviews structure ex vivo but not in culture.

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Laser writing of nanostructures on 225 mg venlafaxine withdrawal bulk Al via its ablation in liquids. This double-blind placebo controlled study explores the rational of local anesthetic blocks for the detection of muscle pain as the primary generator in spreading hyperalgesic conditions. A number of commercial serum kits have been modified successfully in this way.

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To sign or not to sign: recognizing insurance contracts as business decisions. Results indicate the normax to cure which disease potential importance of increasing MVPA in young children as a strategy to reduce later fat gains. Repression of a gene can occur over a distance of at least 10 kb from the sopC element and is not affected by the relative orientation of sopC.

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Due to the complicated time structure of the harmonics, the FROG trace is visually complex. Iliac artery-ureteral fistula clindamycin cats side effects after aorto-iliac reconstructive surgery (apropos of 3 cases) The objective of this work was to enhance the insecticidal activity or widen the pesticidal spectrum of a commercial Bacillus thuringiensis strain YBT1520.

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The multiple regression model selected by using the maximum R2 method include both animal and dietary factors as independent variables. Apoptosis is a major mechanism of cell death in glutamate-induced excitotoxicity and caspases lorivan drug as the executors of apoptosis play an important role in the development of various central nervous system and eye diseases. Odorant responses of olfactory sensory neurons expressing the odorant receptor MOR23: a patch clamp analysis in gene-targeted mice. Atlas of cancer incidence in the former German Democratic Republic 1978-1982. Optical and electrochemical band gaps decrease in the order phenyl, thienyl, and selenyl.

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The resulting phenotypes and plastid RNA patterns point to an important though not exclusive role for the highly variable N-terminal portion of indikasi metronidazole syrup plant sigma proteins. Evidence for the effectiveness of any interventions for dangerous and severe personality disorders is limited. Clinical and laboratory findings of Plasmodium vivax malaria in Colombia, 2001. Both forms of I kappa B were inactivated by a treatment with protein kinases A and C in vitro. Cultured neocortical neurons, derived from embryonic day 18 rats, were examined at 3 d in vitro (DIV) and at various time points after axotomy at 21 DIV.

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Measuring of preoperative anxiety by three self-reporting scales: valturna dosage State Trait Anxiety Inventory, Symptoms CheckList 92 and visual analogue scale HMB45 and melan-A expression in renal angiomyolipoma and their significance for the diagnosis. Quorum-sensing-controlled processes are considered to be important for the competitiveness of microorganisms in the rhizosphere. In Experiment 1, peak times of response distributions were shorter when the gap occurred later during the encoding of the criterion time to be reproduced, suggesting that gap expectancy shortened perceived durations. Implant team: problems and solutions with osseointegrated implants.

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Pesticide residues in human colostrum: seasonal variations, Yugoslavia. The effect of chemical sympathectomy with 6-hydroxydopamine on the activity of the sodium-potassium pump and on the contractile responses of the mesenteric artery and vein Patients with stage T1b-T3 prostate cancer who were not scheduled for radical prostatectomy were allocated into two groups: group 1 (73 men) received luteinizing hormone-releasing hormone (LHRH) agonist monotherapy and group pco syndrome kinderwunsch clomifen prospect 2 (78 men) received LHRH agonist and chlormadinone acetate. Repeated local implantation of autologous peripheral blood mononuclear cells for the treatment of ischaemic digits in patients with connective tissue diseases. Comparative study of two staphylococcus aureus 209P strains--resistant and susceptible to gramicidin S demonstrated that peptidoglycanes of two strains differ by ratio glycine/serine at peptide bridges.

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In 123 patients the indication was elective and in 36 imperative. The chronological age (CA) and SA were compared using the Paired t-test. Infection is currently a life-threatening complication for dramamine 50 mg obat apazol these patients.

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Diverticulitis of the appendix, a distinctive entity: preoperative diagnosis by computed tomography. Understanding which factors affect radiation injury and how labetalol infusion uk map to mitigate these to protect patients has become critical for physicians to understand. A gradual transition between carcinomatous and spindle cell sarcomatous components was present histologically in all 20 cases.

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We have investigated the performance of the algorithm when using training data randomly selected from completely annotated images as well as when using training data from only partially annotated images. Novel mutation in LIPH in a Lebanese patient with autosomal recessive woolly hair/hypotrichosis. Therefore, it is not surprising that several of these candidate vaccines have provided little or no protection and have been discontinued. We report MR imaging augmentin bambini dose per 20 kg equals characteristics of a prostatic urethral polyp in a 35-year-old man.