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Topictal (Topiramate)
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Topiramate

Topictal was prescribed as part of our routine clinical practice, as an add-on medication, or as a replacement of a mood stabilizer. Patients' weight was recorded in 1 to 2 monthly intervals. Patients were followed up for between 6 and 12 months. The final dose of Topictal varied from 200 to 600 mg/day.

Other names for this medication:
Topiramate, Topamax, Epitomax, Letop, Neutop, Piramax, Talopam, Topamac, Topictal, Topigen, Topilex, Topimax, Topina, Topiramato, Topirol, Toplep,

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Topictal is used alone or with other medications to treat certain types of seizures including primary generalized tonic-clonic seizures (formerly known as a grand mal seizure; seizure that involves the entire body) and partial onset seizures (seizures that involve only one part of the brain). Topictal is also used with other medications to control seizures in people who have Lennox-Gastaut syndrome (a disorder that causes seizures and developmental delays). Topictal is also used to prevent migraine headaches but not to relieve the pain of migraine headaches when they occur. Topictal is in a class of medications called anticonvulsants. It works by decreasing abnormal excitement in the brain.

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Recombinant protein assembles into different length polysheaths during expression in the cell, which complicates the preparation of protein crystals for its spatial structure determination. The fungicidal activity of the isolated organisms can be supposed to be mediated by the chromosome. Control of ribonucleotide reductase localization through an anchoring mechanism involving Wtm1. Their performance and selectivity is compared to conventional micellar PSPs with similar structure. The effect of prolonged infusion and withdrawal of angiotensin II in the spontaneously hypertensive rat.

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Analysis of the regulatory region of the bovine X-chromosomal amelogenin gene. Comparable data on the long-term results of bulk bone-grafting done in conjunction with cementless implants are limited.

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To explore the microsurgical techniques for insular glioma without damaging its surrounding normal structures. Plasminogen activator activity (PAA) and plasminogen activator inhibition (PAI) were determined in all spent IVC media. Stimulation of human lymphocytes by allogeneic endothelial cells in vitro. In addition, we discuss the significant side-effects often associated with treatment of heavily infected patients, and the longer-term changes in T-cell reactivity and the host-parasite relationship which follow successful treatment with DEC.

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The goal is to identify small molecular weight compounds that modulate the expression of a target gene in a specific manner, thereby either increasing or decreasing the concentration of the corresponding protein product. The possible consequences of these DNA lesions on the adaptability of H. Contribution of adipose triglyceride lipase and hormone-sensitive lipase to lipolysis in hMADS adipocytes.

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There is increasing need for safe, scalable, and economical alternatives to mammalian cell culture-based manufacturing systems, which require substantial capital investment for new manufacturing facilities. Vitrectomy can be performed to release the anteroposterior and tangential vitreoretinal tractions that sometimes create diabetic macular edema. Trials determining how to modify pulse pressure response to improve survival in the hemodialysis population are indicated. Finally, at the end of 2001, the work of French teams was published concerning the evaluation of risk of relapse for cerebral vascular accident in the presence of a foramen ovale or an aneurysm of the inter-atrial septum.

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Patients with invasive carcinoma in diverticula have an increased frequency of less-common bladder cancer subtypes, and those with pT3 disease are at increased risk for subsequent progression. Value of roentgen diagnosis in recognition of primary and potentially malignant bone tumors Our results indicate the CAT activity was present in tooth germs containing promoter constructs longer than 1.719 kb. Prostate cancer is the most common life threatening cancer in males in Canada, however, relatively little is known about it etiology. Subcellular distribution of ATP-dependent calcium transport in rat duodenal epithelium.

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Life masks and death masks have been used as art forms to mark life passages, offering permanent reminders of family and continuity with the past. The purpose of this study was to investigate the impact of atrial remodeling on the incidence of SCE after AF CA.

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The role of NO resulted from neuronal nitric oxide synthase in the metabotropic glutamate receptor2/3 mediated-brain ischemic tolerance In contrast to avian group A rotavirus, segment 5 was found to migrate closer to 6 as is the case with mammalian group A rotaviruses. Considerable quantities of organochlorine insecticides are still used worldwide and their persistent residues are widely distributed throughout the environment.

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Omega-3 fatty acids improve appetite in cancer anorexia, but tumor resecting restores it. These results suggest that whilst many older women achieve their desired level of DM engagement, some do not, raising the possibility that they may be making choices which are not concordant with their treatment preferences. Magnetic resonance imaging and image analysis for assessment of HPMC matrix tablets structural evolution in USP Apparatus 4. An increase in the concentration of glycogen occurs in the mouse brain after depletion of cerebral catecholamines by alpha methyl-p-tyrosine methylester (H44/68), diethyldithiocarbamate, or reserpine.2. Furthermore, the expression of mu-calpain in tibial nerves was increased following TOCP.

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Six families of the G-protein-coupled receptors comprise most of serotonin receptors besides the conserved 5-HT3R Cys-loop type which belongs to the family of Cys-loop ligand-gated cation channel receptors. To investigate the K-ras gene mutations in asbestos and welding-fumes related human lung cancer (hLC), comparing with the mutational spectrum of K-ras gene in non-occupational hLC, 8 cases of non-occupational hLC, 9 cases of asbestos-related hLC and 4 cases of welding-fumes related hLC were collected. Active coping mediates the association between religion/spirituality and functional well-being in ovarian cancer.

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Thirty patients on finasteride therapy for BPH formed the study group. delta F508 cystic fibrosis mutation appears very infrequently in the Greek-Cypriot community of Cyprus. The results of the present study suggest that Cryptosporidium spp. This process has been successfully applied for the preparation of glucose surface-imprinted nanoparticles.

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Our results suggest that hormonal status and muscle strength have their own separate mechanisms protecting from fall-related fractures. We show here that extracellular matrix (ECM) receptors of the beta1 integrin family regulate myoblast fusion. We included patients who underwent the Ross procedure at our institution between January, 1995, and December, 2003, and in whom we had performed pre- and post-operative exercise stress tests. Remarkably high concentrations of cadmium (5-160 mg/kg) have recently been found in kidneys obtained from penguins living in Antarctica.

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Multilabeling technique was performed on hemimandibles of 3 wk and 3 mo-old scleraxis-GFP transgenic mice for CD146, CD31, NG2, osterix and bone sialoprotein. Pathogen-Specific T Cell Polyfunctionality Is a Correlate of T Cell Efficacy and Immune Protection.

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The Web-based-store-and-forward telemedicine PIHCP allows for remote diagnosis. 2009-2010 National Health Law Moot Court Competition: best brief. Mathematically modeled, they consist of an overdamped second-order system with elastic, viscous damping and mass elements.

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These results support hypothesis that IL-2 may be a good indicator to identify a subgroup of individuals (polymorphism) who differs in Cu metabolism. Post surgical tissue samples were taken from the normal and tumor sections of the tissue. Packaging of an AAV vector encoding human acid alpha-glucosidase for gene therapy in glycogen storage disease type II with a modified hybrid adenovirus-AAV vector. The aim is to train the network to recognize complex phenotypic patterns that are characteristic of those with alcoholism as well as those who are free of symptoms. Furthermore, this model provides a rationale for how the stabilization of the G-quadruplex or i-motif structures formed within the c-myc gene promoter region can inhibit NM23-H2 from activating c-myc gene expression.

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Deletion of the Brd gene complex results in ectopic endocytosis of Dl in dorsal cells of stage 5 embryos. Although cerebrospinal fluid leaks and meningitis are well-known complications, tension pneumocephalus is not well described. Sepsis resulted in a two- to threefold increase in both mRNA and protein levels of UCP3 in skeletal muscle. All vital structures including the facial nerve, carotid artery and vagus nerve preserved.

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We also performed the same analyses on sections of peripheral lung obtained from an additional seven subjects undergoing lung resection. Novel laminin 5 gamma 2-chain fragments potentiating the limbal epithelial cell outgrowth on amniotic membrane. This depression could be to some extent reversed by elevation of the level of L-tyrosine. colubriformis, the third moult appeared by 4 days after infection (DAI) and the last moult occurred between 10 and 11 DAI.

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subiculum and central amygdaloid nucleus) and brainstem nuclei (e.g. Role of a specific endogenous fatty acid fraction in the coupling-uncoupling mechanism of oxidative phosphorylation of brown adipose tissue. Once considered a pharmacological curiosity, allosteric modulation of seven transmembrane domain G-protein-coupled receptors (GPCRs) has emerged as a potentially powerful means to affect receptor function for therapeutic purposes. After Blumeria inoculation, an increase in the proportion of abnormal papilla formation, with an unusual wide halo made of vesicle-like structures, was found in exo70B2 mutants. Explaining additional variance in performance will require incorporating these variables into future studies.

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Diagnostic accuracy and test-retest reliability of nonword repetition and digit span tasks administered to preschool children with specific language impairment. Urea cycle activity and arginine formation in rainbow trout (Salmo gairdneri) Flow cytometric DNA analysis of fine-needle aspirates of prostatic benign lesions. The Hartmann procedure is the surgical treatment of choice for perforated diverticulitis.

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Organisms containing this sequence were observed in enrichments by in situ hybridization. Formation of organic crystalline nanopillar arrays and their application to organic photovoltaic cells. The impact of intravascular devices on nosocomial blood-stream infections in our hospital was high

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Experimental production of congenital malformation of the central nervous system in rat fetuses by single dose intragastric administration of ethylenethiourea. All three major complexes were isolated from milk, other bovine sites, and the environment. A gene responsible for vegetative incompatibility in the fungus Podospora anserina encodes a protein with a GTP-binding motif and G beta homologous domain. We have investigated the effect of CD4 triggering on T cell activating signals in a lymphoma model using monoclonal antibodies (mAb) which recognize different CD4 epitopes.

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Besides, this work shows potential value to design model-based feedback controllers for epilepsy treatment. This was a prospective, nonblinded interventional trial, in a convenience sample of patients 3 to 18 years of age seen in a tertiary care pediatric ED.

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At present in Japan, there are neither reports on antibiotic prophylaxis regardless of underlying diseases nor precise guidelines on prophylactic antibiotics in orthopedic surgery. An increasing amount of data shows that, via certain signaling pathways, epigenetic mechanisms, including DNA methylation, histone modification, and miRNAs, are closely related to the three primary processes that characterize SSc: vascular abnormalities, activation of immune system, and excessive extracellular matrix deposition. Diagnostic safety of vertebral venography in lumbar intervertebral disk displacement Postoperative results and complications in the first 124 eyes are presented.

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Metformin in the treatment of type 2 diabetes in overweighted or obese patients Overweight and obese youth attending specialist obesity services have a high prevalence of vitamin D deficiency. An impedimetric microelectrode-based array sensor for label-free detection of tau hyperphosphorylation in human cells. Self-reported functional ability and pain, and to a lesser extent, stiffness (but not knee and hip ROA), have a modest but independent association with physiological predictors of falls risk. Cisplatin-induced activation of p53 repressed TauT and overexpression of TauT prevented the progression of cisplatin-induced apoptosis and renal dysfunction in TauT transgenic mice.

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Energetics of proline racemase: racemization of unlabeled proline in the unsaturated, saturated, and oversaturated regimes. A methodical system for anthocyanin identification by HPLC-ESI-IT-TOF-MS without the use of standards was also reviewed and applied. Parameters governing gold nanoparticle X-ray radiosensitization of DNA in solution. Antiplatelet, antithrombotic, and lytic therapy for unstable angina, and the appropriate role of revascularization.

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Dendritic morphology is altered in hippocampal neurons following prenatal compromise. These findings provide support for the hypothesis that Abeta is one of the key pathogenic components in IBM pathology and subsequent skeletal muscle degeneration. Furthermore, MBF1 protein level increased in two animal models of hypertrophy, angiotensin II treatment and aortic banding.

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We hypothesized that giving the first dose of RRV-TV vaccine during the neonatal period might reduce the reactogenicity of RRV-TV vaccine without compromising the utilization of the vaccine. However, natural images exhibit additional features, such as particular relationships between local Fourier or wavelet transform coefficients.

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Optical trajectories occur near the interface of the volume with its surroundings, making their performance strongly dependent upon interface quality. A catheter technique was developed to overcome current challenges in the stabilization and manipulation of catheter in tortuous arteries such as right subclavian artery and left common carotid artery. The event-related potential (ERP) technique was used to investigate the neural dynamics in processing different levels of the hierarchical syntactic structure during comprehension of Chinese sentences with the ba construction.

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The remaining VCAM-1-deficient embryos survived to embryonic day 11.5-12.5 and displayed several abnormalities in their developing hearts including a reduction of the compact layer of the ventricular myocardium and intraventricular septum. Graphical abstractCompounds isolated from Helichrysum species (Compositae).

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Ilizarov fixation seems to be an effective method in the treatment of aseptic hypertrophic clavicle nonunions, even in patients where previous surgery has failed. The fetal origins hypothesis suggests that an adverse prenatal environment, indexed by low birthweight (LBW), may increase the risk of developing later disease. The diagnostic characteristics and surgical treatment of acute cholecystitis in middle-aged and elderly patients In contrast with type A NPD, a severe neurodegenerative disease of infancy, type B NPD patients have little or no neurodegeneration, and frequently survive into adulthood.

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Yield of ultrasonography-guided transrectal biopsy in the diagnosis of carcinoma of the prostate The long-term risk of recurrence was lower when we used the 10mm-tip catheter and the survival free of a second procedure was higher among patients treated with this catheter. The results show that projections from the RSG to the retrohippocampal region are as massive as those from the RSA, and that each retrosplenial area has distinct projection fields in the retrohippocampal region. The Jak family of tyrosine kinases are also an integral component in these signalling cascades. In contrast, a recent developmental neurotoxicity study, carried out according to international guidelines, has provided no evidence of adverse effects on neurodevelopment, and this should be considered in a future re-evaluation of BDE-209.

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Overall, we evaluated 208 participants from the four RCTs that were considered suitable for inclusion in the meta-analysis. Radio frequency was applied at five spots with three different time intervals. However, this reversible, probably drug-induced case of hypogammaglobulinaemia highlights the need for immunoglobulin measurements when immunodeficiency is suspected in lupus patients. Furthermore, this conformational change is only partially induced by binding of 4-OH-tamoxifen. Therefore, how to prevent tumor metastasis has been the biggest challenge in cancer chemotherapy.

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Surface activity of the surfactant in experimental compression atelectasis Previous investigations have revealed that perceived spatial frequency of gratings rises as contrast is lowered.

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Magnetic resonance imaging was performed for mandibular muscles and following 2D and 3D measurements were done: cross-sectional area (CSA), thickness, width, longitudinal dimension and volume. Shewanella oneidensis MR-1 has the metabolic capacity to grow anaerobically using Fe(III) as a terminal electron acceptor. The most common bacteria in solitary bee species are a widespread phylotype of Burkholderia and the pervasive insect associate, Wolbachia. In this work, we explore the role of hydrodynamic effects on spinodal decomposition kinetics via continuum simulations of a convective Cahn-Hilliard equation for membrane composition coupled to the Stokes equation.

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The Student t test, variance analysis, and stepwise multivariate regression methods were used to test the impacts of different risk factors on quality of life. Nevertheless, radiation is associated with significant side effects. In correspondence with FAG classification the CNV membranes were localized in different positions in relation to the RPE.

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Although interleukin-6 (IL-6) regulates progression of atherosclerosis, little is known about the relationship of P. Localization pediatric augmentin dose otitis media of recording sites within the SPON provides evidence for a medial (high frequency) to lateral (low frequency) tonotopic representation of frequencies within the nucleus. A fifth IUDR-resistant isolate induced TK similar to the IUDR-sensitive isolates.

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Even the intersystem crossing rate is significantly increased with respect to that of the fulgram 500 mg indicaciones model one. Implementation of a validated HACCP system for the control of microbiological contamination of pig carcasses at a small abattoir.

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In addition to aortic dissection, such entities include intramural hematoma, penetrating aortic ulcer, and localized intimal tear without dissection. Reduced effect of glare disability on driving performance in patients with blue light-filtering intraocular lenses. Furthermore, we examined whether there was a difference between temperature diffusion in normal lung tissue and tumor tissue during laser ablation. VCAM-1 expression manfaat dofen forte was also inhibited when CORM-3 was added 24 h after TNF-alpha stimulation or when TNF-alpha was removed.

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This review provides an overview dutasteride vs finasteride study of the biosensor technology available today, areas which are currently being developed and researched for cancer markers diagnosis-and a consideration of future prospects for the technology. to assess knowledge of human papillomavirus (HPV) and perceived barriers to being vaccinated against the virus.

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Metabotropic glutamate receptor-dependent long-term depression (mGluR-LTD) in hippocampal area CA1 is a form of synaptic plasticity that relies on dendritic protein synthesis. Interleukin 10 inhibits allogeneic proliferative and cytotoxic T cell responses generated in primary verapamil dose for svt site mixed lymphocyte cultures. The 2D spectroscopy, in principle, should reveal more details about the fluctuating environment than the 1D approaches due to peak extension into extra dimension. To review the pharmacological agents that have been developed for the treatment of perennial rhinitis.

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These results show that uncaria can inhabited the synaptic transfer activity of CNS remarkably, suggest that it has the distinct effect of anti-epilepsy. Flecainide in the treatment of nonsustained ventricular tachycardia. However, the National Institute for Neurological Disorders and Stroke criteria for initiation of thrombolytic therapy, most notably the 3-hour time limit from symptom onset, have proven challenging for many rural hospitals to achieve. If this were the case, the gradual normalization ropark dosage index of CSPG proteins over time postinjury would suggest that this may be temporally as well as regionally limited.

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This paper discusses hemisection, an alternative to extraction in cases of vertical root fracture in patients capable and willing to carry jantoven medicine out proper oral hygiene measures. Trials of interventions demonstrate improvement in some outcome measures, but conclusions and generalizability are limited. Annexin-V, Mito-Tracker staining, and inflammatory infiltration were also evaluated.

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To help eliminate rubella in Japan, additional initiatives need to target Japanese individuals who cannot envisage a direct benefit from vaccination. In this paper, the possibility of electron-transfer and subsequent electron transport across membrane proteins (ion channels) is studied with respect to the ion channel function. Administration of the augmentin 375 tablets peptide to mice undergoing an acute inflammatory response reduced the extent of neutrophil transmigration to the site of inflammation, demonstrating the utility of this compound as a potential therapeutic.

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Study of rat liver transplantation from non-heartbeating cadaver donors. Engineering building blocks hgh dose calculator for amoxicillin for self-assembling protein nanoparticles.

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These findings complement our previous work showing that CMV-induced changes in host plant chemistry alter patterns of aphid recruitment and dispersal in ways conducive to virus transmission. Moreover, punicalagin impaired multinucleation and actin-ring formation in OCLs, and decreased the protein levels of nuclear factor of activated T cells cytoplasmic-1 (NFATc1), which is a master regulator of OCL differentiation, and concomitantly reduced the expression levels of Src and cathepsin K, which are transcriptionally regulated by NFATc1. However, migration was blocked by inhibitors of the MEK/ERK pathway, with no effect on cytoskeletal reorganization. Members of the cytosolic acyclovir 400 mg tab ranbaxy eriacta glutamine synthetase gene family are regulated in response to plant nitrogen status, as well as to environmental cues, such as nitrogen availability and biotic/abiotic stresses.