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Laprilen (Enalapril)
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Enalapril

The main aim of this study was to examine the effects of an angiotensin converting inhibitor, Laprilen, and an alpha-1 (alpha-1) antagonist, doxazosin, on albumin excretion, renal haemodynamics and tubular function in insulin-dependent diabetes mellitus patients with nephropathy.

Other names for this medication:
Enalapril, Acepril, Hypace, Iecatec, Innovace, Innozide, Insup, Kintec, Korandil, Lapril, Laprilen, Lerite, Linatil, Lotrial, Maxen, Megapress, Nacor, Nalabest, Nuril, Olivin, Pharmapress, Pres, Prilace, Reca, Renapril, Renil, Renitec, Selis, Tenace, Tenaten, Tencas, Unipril, Vasopril, Vitobel,

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Laprilen is used to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. It is also used to treat heart failure. Laprilen is an ACE inhibitor and works by relaxing blood vessels so that blood can flow more easily. OTHER This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional. This medication may also be used to help protect the kidneys from harm due to diabetes.

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In Saccharomyces cerevisiae, DDT is mediated by the RAD6 epistasis group of genes, consisting of two parallel pathways: error-prone translesion DNA synthesis (TLS), and error-free lesion bypass. Two of four patients treated with vertebroplasty had long-term pain relief. HECS as a source of standard hematopoietic growth factors can be used in the expansion of stem cells in vitro and in the therapy of hemopathy.

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TEE is an efficient technique in MVP non invasive diagnosis and particularly sensitive to posterior MVP. Rituximab could be a valuable treatment option in pegylated interferon related immune thrombocytopenia, when patients are resistant to conventional treatment or when physicians are reluctant to administer corticosteroids.

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On August 13, 1968 Canada experienced its first outbreak of anaplasmosis. The high capital expenditure and the cost of consumables, notably the argon-fluoride gas, makes it imperative to achieve maximum utilization in terms of number of cases treated per fill of gas. The different assays demonstrated that culture-expanded chondrocytes have the potential to form cartilage in pellet mass cultures, to form adipose cells in dense monolayer cultures, and to form a calcium-rich matrix in an osteogenic assay. We retrospectively reviewed clinical data from 1714 patients who underwent colorectal cancer resection from September 2006 to August 2009 at the Korea University Medical Center.

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The term electroosmotic flow refers to the bulk flow of an aqueous solution induced by the application of the electric field to the zeta potential. Ab initio studies for the photodissociation mechanism of hydroxyacetone.

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The purpose of this study was to identify the genetic mechanism underlying capsinoid biosynthesis in S3212, a low-pungency genotype of Capsicum frutescens. The effect of parity of the dam on sexual maturation, serum concentrations of metabolic hormones and the response to luteinizing hormone releasing hormone in bull calves. Visual disorders among preschool-aged children are common, yet screening is infrequent. We study the light emission from a Ag(111) surface when the bias voltage on a scanning tunneling microscope (STM) junction is ramped into the field emission regime.

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However, knockout mice had normal systolic function and mild ventricular hypertrophy but tolerated cardiac ischemia poorly and developed myocardial necrosis threefold more severe than that found in wild-type mice. Both thioesterase activities rose markedly prior to the onset of lipid accumulation, but the induction kinetics suggest that the activities reside on distinct polypeptides. The results of the study showed that orexin A application at the medial preoptic area increased sexual arousal as well as the copulatory performance. Histological evaluation of all 4 polyps showed similar features.

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Metagenomics was used to characterize viral genomes in clinical specimens of horses with various organ-specific diseases of unknown aetiology. The presence of large anatomical variations in individual patients may make it difficult to implicate rectus muscle malposition as an important etiology of A- and V-pattern strabismus. Bicyclomycin sensitivity and resistance affect Rho factor-mediated transcription termination in the tna operon of Escherichia coli.

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Assessment of process variables on 2-ethylhexyl palmitate production using Novozym 435 as catalyst in a solvent-free system. Alcoholic liver disease (ALD) is characterized by accumulation of neutral lipids in hepatocytes leading to micro and macro-vesicular steatosis and balloon cell degeneration. Whereas the binding of HABP1 toward HA is enhanced on increasing the ionic strength, no significant effect was observed with the two other ligands, C1q and mannosylated albumin.

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It is remarkable, however, that the first appearance of the bacoid caryopsis in bamboos might be associated with historical preferences for warmer and wetter climate during the Miocene. Influence of carcinogenic nitrosamines on the induction of serine dehydratase in the rat liver Hypertensive men and women with high HR have significant PP amplifications, principally because of reduced central SBP and disturbed wave reflections. In the event of the premature release of P2X2 TM1 from the ER translocon, the truncated polypeptide fragment was to found aggregate in the ER membrane, suggesting a distinct physiological requirement for the delayed release of TM segments from the ER translocon site.

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This model supports the restriction imposed by National Institute for Health and Care Excellence (NICE) on DMF in HA RRMS and highlights the importance of considering different sub-groups of multiple sclerosis when performing health economic analyses. A series of 2-(3-aryl-2-propenoyl)-3-methylquinoxaline-1,4-dioxides 3a-l were prepared by condensation of various aryl aldehydes with 2-acetyl-3-methylquinoxaline-1,4-dioxide 2. Brain inflammation plays a central role in numerous brain pathologies, including multiple sclerosis (MS). If so, this is only the second reported individual with this disorder and the first instance of its recognition in a child.

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The PFS rate after radiosurgery was equivalent to that after resection of a Simpson Grade 1 tumor and was superior to Grade 2 and 3-4 resections in our study. Patients with APS develop significant morbidity and mortality despite current therapy. The multiplication of Mycobacterium leprae in foot pads of experimentally-infected mice was suppressed by intramuscular administration of ampicillin combined with sulbactam or YTR-830H, two potent inhibitors of beta-lactamase in the bacteria.

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Bacteroides fragilis adheres to laminin significantly stronger than Bacteroides thetaiotaomicron and other species of the genus. Known as the Oklahoma 2001 Healthcare Initiative, HB 2019 has as one of its main purposes the improvement of the public health care system (i.e. The water-soluble porins lost their associated lipids and sterols and are unable to form channels in lipid bilayer membranes.

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The authors reviewed the literature regarding inhalation and ingestion of orthodontic appliances and suggest ways to manage and prevent these events. Comparison of the significant differentially expressed genes from each subgroup relative to the control group reveals differentially expressed genes unique to each subgroup as well as genes in common across subgroups. Two isolates of Paenibacillus validus (DSM ID617 and ID618) stimulated growth of the arbuscular mycorrhizal fungus Glomus intraradices Sy167 up to the formation of fertile spores, which recolonize carrot roots.

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Legionella feeleii has been implicated by serologic studies as the causative agent in an outbreak of Pontiac fever and has been recovered from an institutional water source. Reptiles, including 14 bearded dragons (Pogona vitticeps), 4 blue-tongued skinks (Tiliqua gigas), 8 Burmese star tortoises (Geochelone platynota), 10 Indian star tortoises (Geochelone elegans), 5 red-tailed boas (Boa constrictor), and 5 Northern pine snakes (Pituophis melanoleucus melanoleucus), were manually restrained, and a single blood sample was obtained and divided for analysis. In vitro colony assay revealed that the combination of PSK and any of GM-CSF, IL-3 or stem cell factor (SCF) showed a greater increase in colony numbers than when these materials were administered individually, although G-CSF did not show a synergistic effect with PSK.

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These changes might be an event in the mechanism leading to the decreased lymphocyte proliferative response in vitro and to other immunological dysfunctions reported in old subjects. This review addresses the differences between the groups and the propensity for intergroup and intragroup adverse reactions based on the available literature. We further designed two sets of TaqMan polymerase chain reaction (PCR) primers and probes that can react specifically to goat and sheep mitochondrial 12S ribosomal RNA (rRNA) genes. The nucleotide sequence of a 27,588-bp region of rice mitochondrial DNA was determined.

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For the characterization of the process, we focus on the influencing parameters like the lipid concentration, the injection hole diameter, the injection pressure, the buffer flow rate, and system performance. The aims of this study are, first, to provide a comprehensive description of the somatosensory characteristics of people with pain associated with knee OA. Many different control mRNAs have been employed over the years, but no systematic study has proven their applicability to comparisons made between tumor cells and normal tissues.

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A protein-protein docking algorithm dependent on the type of complexes. For patients with lower CA, the success rate of NLD probing through the upper canaliculus appears to be lower.

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Differences between groups for the SEC were best explained by fear avoidance beliefs about work. Genetics of kidney development: pathogenesis of renal anomalies. Since PfMSP7 could prevent interactions between P-selectin and its leukocyte ligands, these results provide a possible mechanism for the known immunomodulatory effects of both MSP7 and P-selectin in malaria infection models. Compared to rGO, GO showed a higher ability in quenching intrinsic fluorescence of serum proteins in a concentration-dependent manner.

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The plate-based assay displayed three- to 10-fold lower LOD values than did the bead-based assay. Role of cyclic nucleotides and nitric oxide in blood mononuclear cell IgE production stimulated by IL-4. However, the reason for COX-2 overexpression is not fully understood.

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Response to high osmotic conditions and elevated temperature in Saccharomyces cerevisiae is controlled by intracellular glycerol and involves coordinate activity of MAP kinase pathways. The macroscopic findings post mortem enabled a classification of equine gastric ulceration to be suggested (Types 1, 2, 3), according to severity. Epistatic influences of the tumor necrosis factor-alpha and interleukin-1beta polymorphisms. Although it is difficult to assess the extent of the efficacy without a proper or historical control group for comparison, the present study indicates that in children with severe thoracic insufficiency syndrome, the insertion of VEPTRs with multiple expansion thoracoplasties is beneficial over time, by allowing the lungs to expand with body growth without further deterioration in lung function.

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Recognition of AIB in somatoform disorders is important in order to avoid unnecessary tests, inappropriate treatment, and to prevent encouragement and reinforcement of abnormal behaviours. The records of 27 OCD patients with admission both in adolescence and adulthood were compared to a group of manic-depressive and schizophrenic patients with an admission in adolescence where the OCD diagnosis had been given. Hepatic abscess is a very rare consequence of primary TB infection but has never been described as occurring as part of a paradoxical reaction. The results indicate that the catalyst structure as well as the catalyst composition had significant effect on the carbon nanotubes growth. Hysteroscopic myomectomy is a reliable procedure that is effective in controlling abnormal uterine bleeding.

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The addition of continuous femoral catheter infusion of ropivacaine to a continuous popliteal catheter infusion improved postoperative analgesia during movement after major ankle surgery. This methodology should greatly facilitate reverse genetic studies in T. Unique aspects of the colicin channel system are the involvement of protein import in the gating process, the existence of multiple open and closed states, and the existence and action of an immunity protein that involves specific intramembrane helix-helix interactions with transmembrane helices of the colicin channel-forming domains. The upregulation of TIMP-1 following an excitotoxic injury has recently been hypothesized to be part of a general neuronal response that mediates long-lasting changes involved in tissue reorganization and possibly neuroprotection. Liposoluble vitamins and naturally occurring carotenoids in porphyria cutanea tarda.

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Bogomolets Institute of Physiology, Institute of Molecular Biology and Genetics (Acad. The purpose of this study was to determine whether microbial invasion of the amniotic cavity (MIAC) and parturition (term and preterm) are associated with changes in the amniotic fluid concentration of LBP. It seemed useful to collect the elements of correspondence and writings reflecting their common concerns,frequent meetings and friendship. Many aspects of RNA editing in the mitochondria of higher plants are still unknown. Northern blot analysis revealed that TRUB1 mRNA is widely expressed in various human tissues (especially heart, skeletal muscle and liver).

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The healability of the PAA/PEO films originates from the reversibility of the hydrogen bonding interaction between PAA and PEO, and the tendency of films to flow upon adsorption of water. We show that phosphate-free P protein expressed in bacteria is transcriptionally inactive when reconstituted with L protein and viral N-RNA template free of cellular protein kinase. Effect of acaricide resistance on reproductive ability of the honey bee mite Varroa destructor. The high mobility group-containing Sox family of transcription factors constitutes one of the earliest classes of genes to be expressed during embryonic development.

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The slowly hydrolysable is the difference between total biodegradable COD and the sum of readily biodegradable and rapidly hydrolysable COD. Moreover, there was no marked natural fluctuation of skin impedance in the human body and the distribution of LSIPs was considerably stable, which could be plotted on any day in the experiment. The blood level of erythropoietin (Epo) is often anomalously low in anemic patients with inflammatory or malignant diseases.

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Cellular folate vitamer distribution during and after correction of vitamin B12 deficiency: a case for the methylfolate trap. The peak blood levels of secretin that induce Fos protein expression in rat brain are similar to the peak blood levels observed during i.v.

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The microscopic anatomic studies of the temporal bone are one of the greatest help to prevent lesions during surgical intervention. Insufficiency subchondral fractures are nontraumatic flattened lesions in the superolateral area of the femoral head, occurring in healthy adults. Investigation revealed multiple potential sources for contamination during the product cryopreservation process. According to the behavior psychology analysis of the partial mechanical injuries in high-falling death cases, the presumption of high-falling death is usually accurate

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Sirolimus (Rapammune, rapamycin, RAPA) is a strong immunosuppressive agent that reduces kidney transplant rejection. Here, we discuss the most recent findings elucidating the molecular mechanisms and the transduction pathways involved in the regulation of the AKAP-Lbc signaling complex inside cells. In this study, the efficacy of different cryopreservation protocols based on platelet (PLT) recovery was evaluated. Increased precipitation and consequent increase in freshwater inflow is predicted to decrease salinity in some areas of the Baltic Sea. Although the value of pharmacogenomics to improve patient outcomes has become increasingly clear, adoption in medical practice has been slow, which can be attributed to several factors, including complicated and expensive testing procedures and required equipment, lack of training by private practice physicians, and reluctance of both private and commercial payers to reimburse for such testing.

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Metastatic adamantinoma responds to treatment with receptor tyrosine kinase inhibitor. Here we have used immunocytochemistry, live-cell imaging and a surface-mediated secretion assay to show that there are two cytokine export pathways in T helper cells. A concern of ecotoxicology is to predict to which trophic levels in biocenoses bioaccumulation of compounds or of elements occurs. Three monomorphic and four highly polymorphic microsatellites of Nectomys squamipes were isolated and characterised in a sample of 141 specimens from eight different Brazilian localities. Only when the code governing immune responsiveness of cancer will be deciphered, new therapeutic strategies could be designed to fit biologically defined mechanisms of immune rejection of cancer.

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Significant hypercalcaemia can cause electrocardiogram (ECG) changes mimicking an acute myocardial infarction. Despite the widespread use of oral anticoagulants derived from 4-hydroxycoumarin, there have been only a small number of well-defined cases of hepatotoxicity. Experimental and theoretical data are compared and show good agreement. The risk of VKD bleeding in breastfed infants with A1AD was high and did not correlate with serum level of conjugated bilirubin at diagnosis. acnes in healthy skin and during pathogenic conditions, as well as the key molecules involved in these functions.

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CYP450 mRNAs did not differ between ischemic and non-ischemic hearts and appeared to be present at similar levels in the left and right ventricles. Descriptive cross-sectional intercept style face-to-face pilot survey. Lymphocytoma cutis characteristically appears as persistent reddish purple papules, nodules, or plaques.

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Furthermore, we found that posttranslational modifications, such as phosphorylation and acetylation, modulate transcription factor activity and therefore also contribute to INSL3 promoter activity in Leydig cells. The outcomes of these trials, combined with advances in the treatment of heart disease, provide us with a framework for antiarrhythmic therapy. Data were systematically collected at baseline, at 14 weeks, and every 6 months thereafter to 4 years or withdrawal. In this paper, the available body of data (genetic, pharmacological, and other) on ASICs will be reviewed and the role of ASIC in normal nociception and other pain sensations will be discussed. Comparisons of methods for linkage analysis and haplotype reconstruction using extended pedigree data.

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Therefore, these young low-income primiparous women could benefit greatly from educational interventions to encourage primary and secondary cervical cancer prevention programs. population, particularly into the possible health effects of low levels of SHS exposure. Both serum and CSF antibodies were of the IgG class while IgM could only be detected in serum samples.

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They have raised profound moral dilemmas of the internal and external market in their present form, such as the practicalities of distributive justice and the enhancement of autonomy--to which are added the preservation of personhood, the values of listening, the maintenance of altruism and the origins of compassion. (3) Neutrophils and cardiomyocytes do not express NOS immunoreactivity in infarcted and normal rabbit myocardium. We show that the surf-4 coding sequence is conserved between mouse and human. Circadian response of annual weeds in a natural setting to high and low application rates of four herbicides with different modes of actions.

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Recent characterization of one OFC patient shed some light on the controversy over whether OFC and BOR are the same disease, and led to the hypothesis that OFC is caused by contiguous deletions of EYA1 and adjacent genes. Consistent with the modulation of Apaf-1 and the release of cytochrome c, EPO also inhibits the activation of caspase-9 and caspase-3-like activities. Sterilization of the wood in boiling water lowered the elastic modulus and modulus of rupture to a level at which the elastic modulus could be better matched to bone. Four patients were managed by open reduction of the radial head and reconstruction of the annular ligament, and four were managed by radial head excision followed by early motion.

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Cardiac fibroblasts are electrically non-excitable cells that respond to spontaneous contractions of the myocardium with rhythmical changes of their resting membrane potential. Changes in blood volume can induce morphometric and morphological alterations in the secretory complex of the myoendocrine cells due to the stretching of atrial walls.

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The Management of Health and Safety Regulations will be operative from the beginning of 1993. This study examined the effects of a ratio of soy protein to animal protein on bone metabolism of rats. This enhanced radioresistance is due to accelerated repair of DNA double-strand breaks (DSB), the most lethal lesion inflicted by IR. This should allow the pressure distributions to be related to specific types of activities. We examined the spatial relation of 43-kD protein and Torpedo dystrophin, which are cytoplasmic peripheral membrane proteins in the nicotinic acetylcholine receptor (AChR)-rich membranes, to AChR.

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Our data indicate that a neuronal circuitry involving glycine receptors in the nucleus accumbens, and, secondarily, nicotinic acetylcholine receptors in the ventral tegmental area is involved in the mesolimbic dopamine activating and reinforcing effects of ethanol. The present study was designed to determine the effect of tyrphostin AG1295, a selective blocker of platelet-derived growth factor (PDGF) RTK, on proliferative vitreoretinopathy (PVR) development. A prospective survey of women receiving PNC at CBHCs from February 2000 to February 2002 was conducted. To evaluate the effects of pharmacological interventions for people with borderline personality disorder. This technique was employed to create an array of 100 nm wide motifs having a hexagonal 2-D crystalline structure, characterized by COOH-terminated nanospots in a CH3-terminated matrix.

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However, in contrast with tetanic LTP, the expression of anoxic LTP is mediated exclusively by NMDA receptors. Pathological investigations were carried out on mastectomy material. Subependymoma is a tumor of the central nervous system, which frequently occurs in the ventricles and rarely in the spinal cord. The proposed system incorporates an automated spatial filtering technique centred coxib 90 mg nifedipine on the common spatial patterns (CSPs) method, an autoscaled and effective signal features extraction which is used for providing an unsupervised biofeedback, and a robust self-paced classifier based on the discriminant analysis theory.

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The aim of this study was to coumadin side effects tiredness and headaches determine the prevalence of the complications associated with TACE therapy and to correlate it with certain risk factors, either well-known or not yet evaluated. It is likely that a combination of these responses explains the chemo-preventive characteristics of Brassicas and that a combination of different cruciferous vegetables will provide optimal protection.

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Trastuzumab-cisplatin conjugates for targeted delivery of cisplatin to HER2-overexpressing cancer cells. This review explores what is known about the prevalence of vision problems and oral health conditions among individuals with ID, presents a rationale for the increased prevalence of doxepin 100 mg dosierung heparin these conditions in the context of service utilization, and examines the limitations of the available research. Long survival experimental embryos showed that induced rhombomeres give rise to a cerebellar phenotype in their transformed alar plates.

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The number of bony depressions, distribution and amount of joint fluid and the presence of bone marrow changes were assessed. Implementation of novel pyrosequencing assays to screen for common mutations of BRAF and KRAS in a cohort of sporadic colorectal cancers. Purification and characterization of phosphofructokinase of Bacillus licheniformis. Regulation of cephalexin 500mg and drinking alcohol gene expression directed by the long terminal repeat of the feline immunodeficiency virus.

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