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Fastic (Nateglinide)

A single dose of Fastic (60, 120, or 180 mg) or placebo was given to eight diet-treated overnight-fasted type 2 diabetic patients and to seven patients 5 min before a standard breakfast. Effect of semicrystalline polymers on self-emulsifying solid dispersions of Fastic: in vitro and in vivo evaluation.

Other names for this medication:
Nateglinide, Starlix, Fastic, Glinate, Incuria, Meglitinide, Starform, Starsis,

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Fastic is used to treat a type of diabetes mellitus (sugar diabetes) called type 2 diabetes. With this type of diabetes, insulin produced by the pancreas is not able to get sugar into the cells of the body where it can work properly. Using Fastic alone, or with metformin or a thiazolidinedione (other types of oral antidiabetic medicines), will help to lower blood sugar when it is too high and help restore the way you use food to make energy.

Many people can control type 2 diabetes with diet alone or with diet and exercise. Following a specially planned diet and exercising will always be important when you have diabetes, even when you are taking medicines. To work properly, the amount of Fastic you take must be balanced against the amount and type of food you eat and the amount of exercise you do. If you change your diet, your exercise, or both, you will want to test your blood sugar to find out if it is too low. Your health care professional will teach you what to do if this happens.

Fastic does not help patients who have insulin-dependent or type 1 diabetes because they cannot produce insulin from their pancreas gland. Their blood glucose is best controlled by insulin injections.

Fastic does not help patients who have already been treated with other antidiabetic medicines for a long time.

Fastic may be used together with metformin or a thiazolidinedione, but should not take the place of these medicines.

Fastic is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Tablet

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Predictor of early diagnosis, diagnosis, or progression of acute kidney injury. The implications of the actin cytoskeleton during oocyte growth are discussed. Lactococcus lactis catalyses electricity generation at microbial fuel cell anodes via excretion of a soluble quinone.

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Production of lambs of predetermined sex after the insemination of ewes with low numbers of frozen-thawed sorted X- or Y-chromosome-bearing spermatozoa. In the nonobese group, the most rapid absorption of 125I-insulin was found from the upper abdominal area and the slowest from the thigh. Possible ways of detecting other unlinked antisense RNA genes are discussed.

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The role of interventional radiology in complications after paediatric liver transplantation. Finally, HMGB1 in combination with microbial products/TLR ligands seems to be associated with increased viral replication in vitro and in vivo. Other mycotoxins, notably sterigmatocystin and fumonisin, also are relatively potent carcinogens for the liver of animals, but little is known about human exposure to them. The aim of this study was to explore ultrastructural characters of the newly formed bone in the correction of cleft palate (CP) bone defect by distraction osteogenesis (DO).

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The cerebral blood flow in patients with chronic renal failure during hemodialysis. Finally, analysis of Tiam family PDZ domain sequences indicated that the PDZ domains segregate into four distinct families based on the residues studied here. The analysis of the excess thermodynamic functions provides evidence of entropic-enthalpic compensations that result in a favorable enthalpic contribution derived from the interaction of c-Fos with PIP2, which exceeds the unfavorable configurational entropy. For injecting multiplicative weight noise during training, we show that the objective function is different from the prediction error of a faulty MLP whose weights are affected by multiplicative weight noise.

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Analysis by immunoelectron microscopy of Sf-9 cells infected with this virus showed that VLF-1 localized to an end region of the nucleocapsid. A cohort of 1 546 223 patients 18 years or older underwent a total of 2 224 070 low-risk procedures, including endoscopy and ophthalmologic surgery, from Apr.

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Reorganization of the integrin alpha2 subunit controls cell adhesion and cancer cell invasion in prostate cancer. Outsourcing credentialing for a busy physician practice brings improvement. New milrinone analogues: in vitro study of structure-activity relationships for positive inotropic effect, antagonism towards endogenous adenosine, and inhibition of cardiac type III phosphodiesterase. The functional significance of coronary artery disease is often inadequately revealed by the solely anatomic information provided by coronary angiography, especially with respect to intermediate-severity stenoses and the complex lesions that result from percutaneous coronary intervention. This was a cross-sectional study of 68 boys and 72 girls (aged 7-9 yr) who have been followed up since 12 wk gestation when their mothers took part in a study of healthy children born in Southampton, United Kingdom.

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Pregnancy in women with chronic kidney disease has always been considered as a challenging event both for the mother and the fetus. With the help of imaging diagnostics a tumour of the right temporal bone was detected. Part of the success of bariatric surgery is thought to be mediated by gut hormones. The protective efficiency of GDNF increases when it is combined with co-factors such as transforming growth factor beta1 (TGF-beta1), a ubiquitous cytokine. To our knowledge, this is the first ophthalmoplegic migraine case presented pretreatment and post-treatment with clinical photographic documentation and an MRI showing enduring thickening of the oculomotor nerve although symptoms and contrast enhancement resolved.

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Melanoma therapy has recently seen significant progress, with several new drugs in phase II/III trials showing promising results. While many animal studies have been conducted which support this relationship, only in the last 10 years have detailed quantitative studies been carried out in patients with vestibular disorders. This is a retrospective analysis of patients undergoing colectomy between June 2009 and March 2010 to evaluate our outcomes with the NVIS technique (surgical approach via a 4-5 cm suprapubic site for inserting trocars/multiport and specimen extraction, with a 5-mm umbilical incision for a single trocar).

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Publishing trends in Chinese medicine and related subjects documented in WorldCat. At 15 min post-tetanization there were no group differences, however at 60 min post-tetanization the slopes of the field excitatory postsynaptic potentials were significantly diminished for the 24, 48 and 72 h sleep-deprived groups (means 30.44, -1.89, 1.47, respectively) as compared with home cage and pedestal controls (means 59.54, 58.42, respectively).

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Diurnal variability of heart rate in paroxysmal ventricular tachycardia: discovery of real clinical importance or only electrocardiographic feature? Nutritional screening and assessment in cancer-associated malnutrition.

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pombe has allowed the localization of centromeres and telomeres throughout mitosis and meiosis. Pyrimidine and s-triazine as structural motifs for ordered adsorption on Si(100): a first principles study. Glasgow Coma Scale (GCS) scores for patients who underwent neurosurgical clipping and endovascular coiling were analyzed preoperatively and each day following the procedure.

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Tissue sampling was performed in May, July, and September, while field measurements were conducted regularly. We found that three steps of NECEEM-based partitioning in the non-SELEX approach were sufficient to improve the affinity of a DNA library to a target protein by more than 4 orders of magnitude. Our subject pool consisted of 75 patients following general surgical and orthopaedic procedures. Although P300 is regarded as cognitive or endogenous, studies have demonstrated that stimulus intensity influences the component.

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Radiolabelled peptides used for peptide receptor radionuclide therapy are excreted mainly via the kidneys and are partly reabsorbed and retained in the proximal tubular cells. Finasteride, not tamsulosin, increases severity of erectile dysfunction and decreases testosterone levels in men with benign prostatic hyperplasia. The effects of mechanical transparency on adjustment to a complex visuomotor transformation at early and late working age. In patients with clinical suspicion but negative tumor marker profile, too, F-18 FDG PET seems to be a reliable imaging tool for detection of tumor recurrence or metastases.

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There was no significant difference between the retention of the studied post and core systems. Structural and functional properties of human plasma high density-sized lipoprotein containing only apoE particles. The aim of the present study was to evaluate whether endothelial-leukocyte adhesion molecule-1 (ELAM-1 or E-selectin) mRNA expression is upregulated in focal brain ischemia.

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The membrane is found to exhibit fractal behavior, and the derived fractal dimension gives a good description of its morphological complexity. Poly(3-hydroxybutyrate) (PHB) synthesis by recombinant Escherichia coli harbouring Streptomyces aureofaciens PHB biosynthesis genes: effect of various carbon and nitrogen sources. An inexpensive plywood device to support the patient for supine or prone operations involving the rectum is described. The performance was checked against a list of criteria with a maximum obtainable score of 9 for each device. Polymorphisms of -28 C/G and -403 G/A in the RANTES gene promoter region, and of 59029 G/A in the CCR5 gene promoter region were detected by PCR-RFLP (restriction fragment length polymorphism).

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French viewpoint on the introduction of cyclamates into nutrition Two-dimensional acceleration, velocity, and movement can be calculated by a computer. In early autumn, rain events removed soil dust and leaf functions partly recovered, while cement dust created a crust partially remaining onto the leaves and causing more permanent stress. Ferritin is a large multifunctional, multisubunit protein with eight Fe transport pores, 12 mineral nucleation sites and up to 24 oxidase sites that produce mineral precursors from ferrous iron and oxygen.

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Antioxidants prevent health-promoting effects of physical exercise in humans. Molecular biology of Ganoderma pathogenicity and diagnosis in coconut seedlings. These truncated transcripts would be expected to be retroposition-incompetent forms.

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In daily routine, clinically orientated physicians are confronted with various, often highly sophisticated medical devices. Spontaneous production of chemokines by TCCs was evaluated by ELISA. Genetic mapping of the Sorghum bicolor vp1 gene and its relationship with preharvest sprouting resistance.

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The prospective study spanned 6 months between January and June 1998 to determine the incidence of blood splashes to the masks and goggles of surgeons, assistants, and scrub nurses. Hearing levels in infants and young children in relation to testing technique, age group, and the presence or absence of middle-ear effusion. Comparative in vitro activities of several antimicrobial agents against Helicobacter pylori were evaluated.

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Morphological imaging, based on the use of various techniques including ultrasound, X-ray computed tomography (CT), and magnetic resonance imaging (MRI), plays an important role in the characterization, diagnosis and follow-up of patients with human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS). Tap water versus sterile saline solution in the colonisation of skin wounds. If one uses a technique to adjust a single running 10-0 nylon suture in the early period after keratoplasty, the suture tension can be redistributed and astigmatism reduced. Despite advances in surgical and medical therapy, its survival rate remains poor.

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Our density functional theory calculations demonstrate significant surface reorganization for both the bare cluster and the cluster capped with amine or phosphine oxide model ligands. The gene or genes involved in the recessive forms of the disease remain elusive, though genes whose products are required for telomere maintenance are strong candidates. Clinical experimentation with aztreonam in infections of the urinary tract These analyses provide insights into potential strategies to reduce Gram-negative BSIs.

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Obesity in children with developmental and/or physical disabilities. FK506-Binding Protein 10, a Potential Novel Drug Target for Idiopathic Pulmonary Fibrosis. Studies on the effects of mitogens on the primary immune response in vitro. Moreover, for any given age of childbearing, mothers with a higher qualification are more likely than those without to have another child, and are more likely to do so quickly. The transport capacity increased linearly with increasing concentrations of sodium up to 140 mmol/l, whereas the affinity for 5-HT was enhanced at concentrations of sodium up to 100 mmol/l, but reduced at 130 mmol/l sodium.

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A brief review of the clinical consequences of craniofacial anomalies and possible therapeutic modalities is undertaken. The screen is a film assay of luminescence during embryogenesis.

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