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Aponal (Doxepin)

Aponal is a prescription medication used to treat adults who are having difficulty staying asleep. It may also be used to treat depression and anxiety. Aponal belongs to a group of drugs called TCAs. These work by altering chemical signals in the brain. This medication comes in tablet, capsule, and in an oral solution form. This medication comes in tablet form and is usually taken once daily at bedtime for insomnia. The capsule and oral solutions can be taken one or multiple times a day. Common side effects of Aponal include sleepiness, nausea and upset stomach. Aponal cream is a prescription medication used to treat itching of the skin. Aponal cream belongs to a class of medications called antipruritics. These work by blocking histamine. Histamine is a substance that causes itchiness, redness, and general allergic reactions. The cream form is to be applied to the affected area 4 times each day with at least a 3 to 4 hour interval between applications. Common side effects of Aponal cream include burning or stinging at site of application. All forms of this medication may cause drowsiness. Do not drive or operate heavy machinery until you know how Aponal affects you

Other names for this medication:
Doxepin, Sinequan, Adapin, Anten, Aponal, Deptran, Doneurin, Doxal, Doxin, Expan, Gilex, Mareen, Quitaxon, Silenor, Sinepin, Zonalon,

Similar Products:
Kaletra, Clindasol, Dizy, Unigastrozol, Atal, Anten, Aciklovir, Tetraciclina, Soprodal, Andrin, Espirone, Climaston, Maclar, Diseptyl, Zotral, Baycip, Augmentin, Eurovir, Dominadol, Zimox, Celtium, Esomeprazole, Parkan, Otrivine, Sergel, Baclon, Dols, Lapikot, Finara, Modiodal, Veega, Zimaquin, Vastina, Prisdal, Vyfat, Septran, Repam, Feldene, Pacitane, Difenac, Tolep, Efonidipine, Tabalon, Moxifloxacin, Diclofen,

Aponal is used to treat anxiety or depression. It is also used to treat insomnia (trouble with sleeping).

Aponal is a tricyclic antidepressant (TCA). It works on the central nervous system (CNS) to increase levels of certain chemicals in the brain.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Tablet
  • Capsule
  • Solution

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Bridge-mediated hopping or superexchange electron-transfer processes in bis(triarylamine) systems. Significant changes in target volumes can occur during SRT for Stage I non-small-cell lung cancer. Development of (153) Sm-folate-polyethyleneimine-conjugated chitosan nanoparticles for targeted therapy.

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The GST (glutathione S-transferase)-tagged QorA protein was expressed in Escherichia coli and purified using a glutathione affinity column. Properties of helminth parasites such as taxonomic group or life cycle and properties of the host population localities such as area size or the stability of the environment (estimated by mammal species diversity) contribute to the nestedness.

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Challenging consults: application of principles of physiology and biochemistry to the bedside. To evaluate the cost-effectiveness of strategies for pulmonary nodule diagnosis and to specifically compare strategies that did and did not include FDG-PET. Sixty-nine patients undergoing elective laparoscopy, inguinal hernia repair, or knee arthroscopy were enrolled. Individual-level variables assessed knowledge related to PA and exposure to the intervention.

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Crude extracts that contain this form of gamma protein are capable of donating FeMo-co to apodinitrogenase, thereby activating the apodinitrogenase. The grapefruit juice-celiprolol interaction is probably of clinical relevance. Thermocycling procedure was performed for simulating temperature changes in oral conditions.

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These data identify a novel target for ERK, and suggest that its ability to stimulate biosynthetic capacity and growth involves direct transcriptional activation of tRNA and 5S rRNA genes. The laser power needed for optimum results in argon laser trabeculoplasty. Based on the morphological, physiological, biochemical and nutritional characteristics, cellular fatty acid and lipid composition, ubiquinone-8 as the major respiratory quinone, guanine-plus-cytosine content of DNA, DNA-DNA homology value, and sequence alignment of 16S rRNA nucleotides, Oklahoma isolate was reidentified as a strain of Pseudomonas pseudomallei. The coronary subclavian steal syndrome: an uncommon sequel to internal mammary-coronary artery bypass surgery. Gamma-secretase is a protein complex containing Presenilin and Nicastrin proteins, which also processes Notch and other receptors involved in the eye and lens development.

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Only 3 percent of persons who reported alcohol use problems alone received such services. Understanding Heterogeneity and Permeability of Brain Metastases in Murine Models of HER2-Positive Breast Cancer Through Magnetic Resonance Imaging: Implications for Detection and Therapy.

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When compared with the standard drug, the net effect of extract is even less than that in Group II. Today, the advanced exploration of alternative cell lines and enhanced cell culture systems, as well as the development of alternative expression technologies, such as transgenic animals, is opening a new era in the production of the full range of recombinant plasma protein therapeutics. We present a case of angioleiomyoma of the distal ulnar artery that presented with painless mass and gradual enlargement. Disseminated infection caused by Nocardia asteroides is a fairly rare entity occurring mostly in immunocompromised states. Treatment of 14 patients with macrolides significantly reduced BAL fluid concentrations of HBD-2 but not HBD-1 or plasma concentrations of HBD-1 and HBD-2.

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To our knowledge, cortical thickness, a measure of particular interest in schizophrenia, has not previously been evaluated in terms of its heritability in relationship to risk for schizophrenia. Cells stably transformed by the Src oncogene tyrosine kinase were examined for STAT protein activation.

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A chest radiograph obtained because of intercurrent infection unexpectedly revealed a left-sided congenital diaphragmatic hernia. Criterium for the diagnosis of idiopathic heart muscle hypertrophy from the electrocardiogram Joint committee on physical fitness, recreation, and sports medicine. However, there is no known reversal agent for this class of anticoagulants. Twenty-four animals received either d- or l-bupivacaine (2 mg/kg) in random order.

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Common CFTR mutations are not likely to predispose to chronic bronchitis in northern Germany. Thirty-four patients underwent percutaneous Achilles tendon repair between 2004 and 2006. The Maxwell stress between magnet and keeper was integral analyzed using the finite element method, and the attractive force between magnetic attachments was obtained. Specifically, Z tests of proportion are highlighted and illustrated with imaging data from two previously published clinical studies. The recent availability of two lamprey draft genomes from sea lamprey Petromyzon marinus and Japanese lamprey Lethenteron japonicum presents an opportunity to infer early evolutionary events of ABC genes in vertebrates.

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To analyze critically refractive surgery of the cornea by excimer laser and to compare laser surgery with other methods of treatment of refractive errors of the eye. The prognosis of postoperative complications in patients with cancer of the large intestine The present case describes a new and unusual variant of thyrotoxicosis: transient hyperthyroxinemia following acute and massive hemorrhage into a previously normal thyroid gland. GH, is also expressed in normal and neoplastic human mammary glands.

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Hydroxylation of thiacloprid by bacterium Stenotrophomonas maltophilia CGMCC1.1788. A three-dimensional analysis of lymph collecting vessels in the breasts, anterior upper torso and the internal mammary vascular bundles was achieved using both plain radiography and CTL.

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A novel minimally invasive endoscopic repair in a case of spontaneous CSF rhinorrhea with persistent craniopharyngeal canal. Validation of a Systemic Lupus Activity Questionnaire (SLAQ) for population studies. Opioid peptides content in the rat brain during the ictal phase and after pentylenetetrazol-kindled rats. The technology available for the endovascular treatment of intracranial aneurysms is rapidly evolving. Since the publication of the mouse genome, attention has focused on the strains that were selected for sequencing.

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We develop a general optimization procedure to determine the existence of optimal swimming gaits and investigate their functional significance with respect to locomotion and nutrient uptake. Altered fractionation and/or adjuvant chemotherapy in definitive irradiation of squamous cell carcinoma of the head and neck.

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Long-term regulation of N-methyl-D-aspartate receptor subunits and associated synaptic proteins following hippocampal synaptic plasticity. The patient had presented with nasal obstruction and headache over a period of approximately 8 months. We report a 45-year-old man who fell and sustained a fracture dislocation of L2 vertebra. Rectal cancer in pregnancy is a rare disease, challenging clinicians as there are no generally accepted guidelines regarding diagnosis or treatment. nerka the NORs were found in an interstitial band on the short arms of one submetacentric chromosome pair and in O.

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This, in turn, provides a further indication that the VEGF pathway and its signaling proteins may be appropriate targets in the management of MM. Vascular angiotensin II resistance with juxtaglomerular cellular hyperplasia and hyperaldosteronism The feeder vessel of the AVM originated from the right middle cerebral artery.

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The percentage of stained area for GLP-1 immunoreactive cells was found to be significantly higher from 200 cm from Treitz ligament onward compared with the first 80 cm of the small intestine, whereas GIP immunoreactive cells were predominant expressed in the first 80 cm. To evaluate effects of apheresis on mesenchymal stem cells (MSCs) and compare those MSCs with MSCs obtained from adipose tissue or bone marrow (BM). To examine the prevalence of pretransplant modifiable, potentially modifiable, and nonmodifiable cardiovascular risk factors in patients who received kidney transplants between January 1, 1994, and December 31, 1996.

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The alpha-subunit co-migrates on one- and two- dimensional isoelectric focussing-SDS polyacrylamide gels with the major polypeptide synthesised by isolated mitochondria. The characteristics of these tumors must be determined to evaluate whether surgery or conservative management is the best therapeutic option.

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Efficacy depends on two factors: the intrinsic equilibrium between active and inactive states in the absence of agonist, and the energy contributed by the agonist as a result of the relative affinities of agonist for the active and inactive states. We demonstrate in a simulation study and a data example that our quasi-likelihood method for spatial point processes is both statistically and computationally efficient. We present a 55-year-old man with a symptomatic large cystic hepatic mass. Fitting the data with an allosteric-kinetic model, together with molecular dynamic simulations, suggests that the presence of the inter-backbone H-bond between positions 152 and 193, revealed in alpha4 and in alpha7 double mutant but not in alpha7, coincides with a large stabilization of both open and desensitized states of nicotinic receptors. Options available for the infusion of lipid emulsion in home parenteral nutrition (HPN): a questionnaire survey for hospitals in Japan where HPN is practiced.

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The temperature characteristics of synaptic membrane ATPases from immature and adult rat brain. leprae-specific phenolic glycolipid I and several protein antigens previously demonstrated to have diagnostic potential were assessed. The wavelet approach can reliably predict the ori and ter regions and the bacterial chromosomes have a strong tendency towards a physical balance between ori and ter.

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Nbr1 binds additionally to proteins implicated in ubiquitin-mediated protein turnover and vesicle trafficking: ubiquitin-specific peptidases USP8, and the endosomal transport regulator p14/Robld3. Thirty four patients of mean age 14.7 years completed both pulmonary function and maximal aerobic capacity tests at 6 months.

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Each group was divided into control group, sodium hyaluronate coating group and triamcinolone acetonide injection group. The advantages of various bronchoplastic operations application after performance of endoscopic recanalization of tracheobronchial tree were noted. Furthermore, relaxin induced the acrosome reaction and, interestingly, the percentage of viable sperm with the acrosome reaction induced by relaxin was similar to that obtained with progesterone. This Account details the evolution of oxidative coupling reactions in our laboratory, from initial concepts to highly efficient reactions, focusing on the practical aspects of performing and developing reactions of this type.

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Internal medicine and the training of international medical graduates: a time for open discussion and new approaches. The discovery of leptin raised the hope that a natural compound had been found that could cause weight loss without adverse effects. The immediate and long-term impact of severe acute respiratory syndrome (SARS) outbreak on emergency department (ED) visits and hospital expenditures for these visits has not been thoroughly investigated.

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However, new classes of drugs have recently emerged that promise better clinical outcomes and lower risks. Additional, postcranial apomorphies (strut-like coracoid, cranially located humeral condyles, olecranon fossa, slender radius relative to the ulna, trochanteric crest on the femur, and ulna longer than the humerus) identify the embryo as avian. Study was conducted in dental pulp tissues obtained from the children in the age range of 5-14 years. Maximal response to a plasma cholesterol-lowering diet is achieved within two weeks.

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VATS represents the approach of choice for both diagnosis and treatment of SPNs. Identification of a 66 kD heat shock protein (HSP) induced in M-14 human melanoma cells by severe hyperthermic treatment. Different formulations were prepared by incubating them at 80 degrees for different incubation times of 5, 10, 15, 20, 25 and 30 min.

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The occurrence of anti-lamin C autoantibodies in one EMS patient expands the spectrum of clinical conditions associated with these antibodies, and provides evidence for an autoimmune response in EMS. Sixty-six male Wistar rats were randomly divided into three groups: control group, hemorrhagic shock and resuscitation group and propofol treatment group.

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It has been shown in experiments on white rats that chronic (for one month) intoxication with CCl4 and C2H5OH results in liver injury. Cytological and cytochemical studies of green monkey kidney cells infected in vitro with simian virus 40. We found that 43 of the 46 SLC families found in Homo sapiens were also found in Caenorhabditis elegans, whereas 42 of them were also found in insects. Despite its simplicity, this analysis can be extended to simulate repeat length-dependent protein unfolding, an event speculated to precede aggregation and disease progression. Our results will lay the empirical foundation for (a) detection of early biopsychosocial markers, (b) development of screening measures, and

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In this, the first published report to describe outcomes of cataract surgery in renal transplant patients, most complications were associated with high of steroids use and immunosuppressives, and were independent of the type of cataract surgery used, either ECCE or phacoemulsification surgery. Lysophosphatidic acid and lipopolysaccharide bind to the PIP2-binding domain of gelsolin. CRH also elicited a late, preferential beta E release which was associated with only an enhanced POMC hnRNA expression. Both differences and similarities in periodontal and hematological variables were seen in individuals with periodontitis, JIA, and RA.

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willing One finds in these patients a readiness to reorder priorities and a willingness to examine and make the most of their lives, and psychotherapy can therefore become an opportunity for positive change rather than just support for a medical catastrophe. ACE I/D gene polymorphisms and AF are significantly related to ethnicity.

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Effects of extracellular pH on the metabolic pathways in sulfur-deprived, H2-producing Chlamydomonas reinhardtii cultures. Megakaryoblasts were classified into the following three types according to the formation patterns of the demarcation membrane. monocytogenes was able to grow in drink A and survived in drinks D and F for at least 2 days. Anterior grafts, using the thoracic route, in treatment of vertebral deviations. Stretch-induced LMW HA from fibroblasts caused a significant dose-dependent increase in interleukin-8 production both in static and stretched epithelial cells.

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Associations between dietary variables and BMI were evaluated with repeated measures analysis of variance modeling. In the first and second experiments, a strong effect of word priming on nonword spelling was found, even when two intervening filler items separated primetarget pairs. Loss of one p53 allele results in four-fold reduction of p53 mRNA and protein: a basis for p53 haplo-insufficiency.

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Histology and immunohistochemistry confirmed that the lesion was RDD. Staining for alpha 1-AT and alpha 1-ACT showed no differences as compared to controls. Effect of phenolic compounds on the polymerization of methyl methacrylate. A regioselective intramolecular cyclization/halogenation reaction of N-alkoxy-o-alkynylbenzamides with CuCl(2)/NCS was developed. The identification of several mammalian proteins involved in Mg transport highlights the physiological importance of this cation and its tight regulation in numerous tissues.

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The second is the differential bias (difference between cases and controls in the difference between mean measured and true exposure) relative to the true difference in exposure between cases and controls. Endothelial dysfunction and LOX-1: forty years from muscle to endothelium. Damage to one or more components within this network may result in impaired voluntary control. Furthermore, when peripheral blood mononuclear cells are incubated with zinc in vitro, the release of cytokines such as interleukins (IL)-1 and -6, tumor necrosis factor-alpha, soluble IL-2R and interferon-gamma is induced. Immunocytochemistry for beta(1)-integrin expression and vinculin was performed on all wounded monolayers.

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three times per week for 8 or 12 weeks reduced testis weight and increased seminal vesicle weight in mice. Follow-up brain CT showed complete resolution of the EDH within 2-3 months. Melatonin (N-acetyl-5-methoxytryptamine) is an indoleamine with a range of antioxidative properties. Analyses of the amino acid sequences deduced from these genes revealed that three (orf12, orf14, and orf22) encoded novel alcohol dehydrogenases of different types, four (orf5, sucB, fdhD, and yabF) encoded novel putative oxidoreductases belonging to groups distinct from alcohol dehydrogenases, one (glpK) encoded a putative glycerol kinase, and one (orf1) encoded a protein which showed no similarity to any other known gene product.

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Targeted interventions that aim to increase knowledge of the benefits and reliability of LARC and allow informed use are recommended. However, several indications of under-registration suggest that the real value is about twice that observed. We questioned whether repeated shock wave application provides a cumulative effect on nerve fibers compared with the effect of one application. In addition to friction caused by skin-to-skin touch, skin folds are warm and moist areas of the skin that have limited air circulation. Like other co-receptors, these proteoglycan signaling co-receptors can bind multiple ligands, promoting the formation of receptor signaling complexes and regulating signaling at the cell surface.

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The wound channel had a downward course and terminated in the superior vena cava at the level of the pericardium, where from the bullet was transported down the inferior vena cava to the right femoral vein. Therefore, the influence of food and beverages ingested during the monitoring period was studied.

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Recently a reported association between p27 and Von Hippel-Lindau (VHL) gene function has also been noted. Role of estrogen receptors alpha, beta alventa drug testing and GPER1/GPR30 in pancreatic beta-cells.

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Developmental (embryo-fetal toxicity/teratogenicity) toxicity studies of synthetic crystalline lycopene in rats and rabbits. Treatment with p-chlorophenylalanine methylester-HCl (PCPA), 400 mg/kg, 24 h before nialamide partially antagonized the increase in motor activity and the accumulation of NA and dopamine was not significantly different from that observed after nialamide alone.4. The effects of specific gabalept tablets comparison cuts or releases of the anatomic portion on joint gaps were investigated.

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Clinical and imaging findings in patients with aggressive spinal hemangioma requiring surgical treatment. The 25-OH-D was significantly lower in the 15-year-old than in the other children, but it was satisfactory in all groups as compared to the 25-OH-D of healthy, young adults. Environment-based interventions have demonstrated positive impact on apathy, flox vs loxp-flanked yet, influential environmental components are largely understudied.

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The quality of the ethanolic extract BNO 1055 (contained in Klimadynon(R) and Menofem(R)) differs from that of combutol 800 medicine dictionary an isopropanolic extract. Immunohistochemistry and diagnostic electron microscopy (UP 10(2)iii, 1986) Fibrinogen differs significantly according to SRH in males only, with low absolute value differences. Adequate capillary supply is a precondition for tissue survival and proper function. All randomised and controlled clinical trials which focus on the use of naltrexone maintenance treatment versus placebo, or other treatments to reach sustained abstinence from opiate drugs

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The wandering ampulla--duodenal-jejunal intussusception of a carcinoid tumour with displacement of the bile duct to the left iliac fossa. Receptor tyrosine kinase (RTK) activation is critical for growth factor-mediated cell proliferation. There is indication that during efflorescence a solid shell grows at the surface of the liquid droplet which finally collapses due to mechanical stress. fenofibrate 200 mg capsule price We conclude that the use of MRI and MRC improves the diagnostic evaluation of patients with hepatobiliary disease.

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Sap-induced vaginitis is an early event during vaginal infection, is uncoupled from fungal growth, and requires Sap and caspase-1 enzymatic activities to occur, suggesting that Sap or products of Sap activity activate an inflammasome sensor of epithelial cells. In addition we present initial evidence that the nonlinear clonazepam 0.5 mg compared to xanax withdrawal phenomena predicted by our model are observed experimentally.

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The management of operated patients using a relational data base Mast zonegran 50 mg nebenwirkungen diclofenac cells (MC) are important effector cells in allergic disorders. Among the 37 patients who rejected theirs grafts, 8 had anti-keratinocytes Ab, 11 had Ab against epithelial-endothelial hybrid cell line, 9 were positive for both tests. This study assessed modifications in ET type 1 (ET-1), ET type A receptor (ET(A)), and ET type B receptor (ET(B)) localization and/or expression in irradiated human rectal tissue and in a rat model of delayed colorectal injury.

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The snap-frozen, cryostat sections were subjected to histochemical reactions for acid phosphatase and alkaline phosphatase. The degree of velopharyngeal closure and the situation and movement of other speech organs can be demonstrated. We show that Xenopus EIG121L (xEIG121L) protein, an evolutionarily conserved transmembrane protein, is expressed in the ventral clopidogrel dosing intermediate metabolizer ectoderm at the gastrula and neurula stages. Furthermore, excessive precipitation of CaCO3 as needled shaped aragonite in the continuous aerobic granular sludge reactor was observed, which led to the further enhancement of settling ability of granules with sludge volume index (SVI) reduction from 32 to 2 ml g(-1) but specific oxygen utilization rate (SOUR) decrease from 61 to 23 mg O2 g(-1) MLVSS h(-1).