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Atazanavir
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Atazanavir

Atazanavir is an oral medication that is used for treating infections caused by the human immunodeficiency virus (HIV). It is in a class of drugs called protease inhibitors that also includes ritonavir (Norvir), nelfinavir (Viracept), indinavir (Crixivan) and saquinavir (Invirase, Fortovase). During infection with HIV, the HIV virus multiplies within the body's cells. Viruses are released from the cells and spread throughout the body where they infect other cells. In this manner, HIV infection is perpetuated among new cells that the body produces continually. During the production of the viruses, new proteins must be made. Some of the proteins are structural proteins, that, is, proteins that form the body of the new viruses. Other proteins are enzymes that manufacture DNA and other components for the new viruses. Protease is the enzyme that forms the new structural proteins and enzymes. Atazanavir blocks the activity of protease and results in the formation of new viruses with defective proteins that are unable to infect the body's cells. As a result, the number of viruses in the body (the viral load) decreases. Nevertheless, Atazanavir does not prevent the transmission of HIV among individuals, and it does not cure HIV infections or AIDS. Atazanavir was approved by the FDA in June 2003.

Other names for this medication:
Atazanavir, Atazor, Reyataz,

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Atazanavir is used together with other medicines for the treatment of the infection caused by the human immunodeficiency virus (HIV). HIV is the virus that causes acquired immune deficiency syndrome (AIDS).

Atazanavir will not cure or prevent HIV infection or AIDS. It helps keep HIV from reproducing and appears to slow down the destruction of the immune system. This may help delay problems that are usually related to AIDS or HIV disease from occurring. Atazanavir will not keep you from spreading HIV to other people. People who receive this medicine may continue to have other problems usually related to AIDS or HIV disease.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Capsule
  • Powder

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Postabsorptive muscle protein synthesis and postprandial protein handling is not impaired in older individuals with type 2 diabetes when compared with age-matched, normoglycemic controls. This adaptation is indispensable in tumor cells-where growth demands and a fluctuating blood supply place unnatural stresses on ER function-and is therefore an attractive therapeutic target. The results confirm postulated mechanisms for viral persistence in the CNS and suggest in addition a possible role of the viral protein H in the pathogenesis of SSPE. Here, we use genome-wide array-based comparative genomic hybridization (aCGH) to profile differential DNA replication in isolated and purified larval fat body and midgut tissues of Drosophila, and we compare them with recent aCGH profiles of the larval salivary gland. With proper diagnosis and treatment of these deficit(s), the symptoms are curable.

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This nanoparticles stimulated insulin secretion from islets in a glucose-dependent manner at streptozotocin (STZ)-induced diabetes. Bacterial adhesion on implant surfaces is the initial step in the infective process. Therapeutic effects of the angiogenesis inhibitor TNP-470 against carcinomatous peritonitis in mice.

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Liver metastases from colorectal adenocarcinoma: does systemic chemotherapy have any value? The androgenic steroid testosterone is well known for its function in reproduction, sexual differentiation and sexual behavior. Prior meniscus injury and pre-injury Tegner activity levels are predictive significant variables for excessive knee joint effusion after ACL reconstruction. Primer extension and in vitro transcription studies revealed that the CcpA regulation of phoPR transcription was due to repression of P(A6), a previously unidentified promoter positioned immediately upstream of the cre box.

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Varieties of fast and slow extrafusal muscle fibres in amphibian hind limb muscles. New variability in cerebrovascular anatomy determines severity of hippocampal injury following forebrain ischemia in the Mongolian gerbil. Patients who use this full-contact brace seem to have fewer complaints of pain, resulting in increased ability to complete functional tasks, work, and play sports. Tx generation by monocytes is triggered by the interaction between fibrinogen and the specific monocyte membrane receptor. However, staining of the vascular endothelium was increased on postoperative day 7 when the total activity was high.

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Efficacy of bone morphogenetic protein (BMP) with osteopromotive membranes--an experimental study in rat mandibular defects. Methods are developed for estimating absolute disease incidence rates by combining passive surveillance data with a cohort study. Septic arthritis in patients with acquired immunodeficiency syndrome with human immunodeficiency virus infection. In conclusion, our data demonstrate steroid hormone responsivity in the adult human brain by revealing neural plasticity in the language domain, which appears hormone, task, and region specific. Human cortical object recognition from a visual motion flowfield.

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Evaluate whether supplementary fibular fixation helped maintain axial alignment in distal metaphyseal tibia-fibula fractures treated by locked intramedullary nailing. Using a strict subject selection procedure, we tested in High and Low Hypnotizable subjects (HHs and LHs) whether treatments of hypoalgesia and hyperalgesia, as compared to a relaxation-control, differentially affected subjective pain ratings and somatosensory event-related potentials (SERPs) during painful electric stimulation. The incidence and severity of exercise-induced asthma were determined in nineteen asthmatic patients who performed eight minutes of exercise following four treatments administered in a random order. Homocysteine is a nonessential aminoacid whose increase is related to the appearance of neural tube defects in humans. Concanavalin A, but not galectins, was also able to stimulate VEGF-C production by low VEGF-C-producing cell lines MCF7 and T-47D.

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The manifold clinical features of central nervous system involvement indicate the pathogenetic importance of neurological involvement in the development of PFH. Amphiregulin antisense RNA expression inhibits efficiently the angiogenesis in breast cancer, suggesting this growth factor could represent a novel therapeutic target in breast cancer. Psammaplins from the sponge Pseudoceratina purpurea: inhibition of both histone deacetylase and DNA methyltransferase. They gave consideration to unique terminology and analyses required for evaluation of correction of astigmatism by laser systems that reshape the comea. ROSETTA3: an object-oriented software suite for the simulation and design of macromolecules.

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Predictors of hemorrhage after laparoscopic partial nephrectomy. Differential pattern of heart rate variability in patients with schizophrenia. The presence of a fistula is a rare occurrence in itself, but the different origins and drainage sites of fistulae are what make them even more rare. First of all, with the introduction of more nucleoside and nucleotide antiviral therapies, it has become clear that variants or mutants do emerge in time. The dura mater encapsulated the cavernous sinus cavernoma, explaining the severe bleeding from the dural incision.

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Magnetic resonance imaging (MRI) is a non-destructive and non-invasive method, the experiment can be conducted in situ and allows the studying of the sample and the different processes in vitro or in vivo. Furthermore, the variety of clinical manifestations identified in our HR patients underlines the extreme clinical and genetic heterogeneity of this disease.

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While it is well understood that nanoparticle (NP) physico-chemical properties can dictate biological responses and interactions, it has been difficult to outline a unifying framework to directly link NP properties to expected in vitro and in vivo outcomes. Experience in treatment of combined osteovascular limb injuries in children This publication reviews the state of the art in monkey models for rheumatoid arthritis and multiple sclerosis and the (few) gene therapy experiments that have been performed in these models. Body build is use of diclofenac sodium in pregnancy the major determinant of kidney weight and nephron size in normal humans.

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Differentiation, development, and function of Leydig cells in the testis are regulated also by macrophages, vascular endothelial cells, and peritubular cells in the testis. Great strides have been made to identify why vestibular schwannomas develop at the molecular level. We studied the influence of storage (1-5 days) and gamma irradiation (0, 25, 50, 100 Gy) on the in vitro aggregability of stored ibarin precious metal prices platelets. The convergence properties of a decomposition method can be guaranteed by means of a suitable selection of the working set and this can limit the possibility of exploiting the information stored in the cache.

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