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Trolip (Fenofibrate)

We randomised 171 participants with type 2 diabetes mellitus, who had been recruited to the FIELD study in Helsinki, to micronised Trolip (200 mg/day) or placebo in double-blind study design. Effects of Trolip on C-reactive protein levels in hypertriglyceridemic patients.

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Fenofibrate, Tricor, Antara, Antilip, Controlip, Craveril, Einecs, Fenocap, Fenofibrato, Fenogal, Fenoglide, Fenolip, Fenoratio, Fenosup, Fenox, Fibral, Fulcro, Lexemin, Lifen, Lipanthyl, Lipantil, Lipcor, Liperial, Lipicard, Lipidcare, Lipidil, Lipirex, Lipofen, Lipsin, Lofat, Lofibra, Nofiate, Normalip, Normolip, Secalip, Stanlip, Supralip, Tilene, Trigent, Triglide, Trilipix, Trolip, Versamid,

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Trolip is used with a low-fat diet, exercise, and sometimes with other medications to reduce the amounts of fatty substances such as cholesterol and triglycerides in the blood and to increase the amount of HDL (high-density lipoprotein; a type of fatty substance that decreases the risk of heart disease) in the blood. Build-up of cholesterol and fats along the walls of the arteries (a process known as atherosclerosis) decreases the blood flow and, therefore, the oxygen supply to the heart, brain, and other parts of the body. This increases the risk of heart disease, angina (chest pain), strokes, and heart attacks. Although Trolip decreases the levels of fatty substances in the blood, it has not been shown to decrease the risk of heart attacks or strokes. Trolip is in a class of medications called antilipemic agents. It works by speeding the natural processes that remove cholesterol from the body.

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Cancer incidence data in these registers could describe long-term effects of interruption of asbestos exposure. The relationship between adherence and illness and medication beliefs was tested at baseline (time 1) and again 5-6 weeks later (time 2).

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During quinidine treatment, the formation of sparteine metabolites (2- and 5-dehydrosparteine) was practically abolished. The in vitro constructed artificial corneas were histologically similar to normal rabbit corneas. Emerging Concepts in the Molecular Basis of Pulmonary Arterial Hypertension: Part II: Neurohormonal Signaling Contributes to the Pulmonary Vascular and Right Ventricular Pathophenotype of Pulmonary Arterial Hypertension. This paper describes a system, DataServer, that permits researchers to query and retrieve data from multiple clinical data sources, automatically deidentifying patient data so that it can be used for research purposes.

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We theorized family functioning to partially mediate the relationship between objective burden and distress and to significantly account for the prediction of distress beyond well-recognized predictors. Associations between hours worked per week and Body Mass Index (BMI), food intake, physical activity, and perceptions of eating healthy at work were examined in a sample of transit workers. Glycine-proline-glutamate (GPE) is naturally cleaved from the IGF-1 N-terminal and it is also neuroprotective after ischemic injury, which provided a novel strategy of drug discovery for neurological disorders.

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Comparison of the pattern of early revascularization of conventional versus vascularized nerve grafts in the canine. Oculoglandular syndrome caused by Yersinia pseudotuberculosis in a dairy goat. Sll1717 affects the redox state of the plastoquinone pool by modulating quinol oxidase activity in thylakoids. 55 patients with echinococcal cysts in the liver were treated surgically at our department between 1987 and 1999.

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This study evaluates the robustness of reinnervation of the larynx using a split-hypoglossal nerve graft in an animal model, with outcomes assessed by independent blinded review. In addition, TNFalpha-treated cell populations are markedly less susceptible to apoptosis by UV irradiation and this cytoprotective effect is at least in part mediated by p21(Cip1/Waf1) as well. The proliferation and invasiveness of these cell lines were assessed. The B43-Gen immuno-conjugate might be useful in eliminating leukemia cells in patients who have failed conventional therapy.

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Both rows of spots in the deglycosylated sample showed a coordinated shift toward the basic side of the gel, and a prominent new spot appeared on the basic end of the lower molecular weight group, which probably represents the fully deglycosylated form of the most abundant X-GP isoform.(ABSTRACT TRUNCATED AT 250 WORDS) The results indicate that the gastric lesion is accompanied by an increase in mucosa-synthesize LTC4, while PGE2 formation remains unchanged. Affected probands and siblings fulfilled DSM-IV criteria for schizophrenia or schizoaffective disorder. The results indicate that the mechanism by which sulphur amino acids protect from cadmium toxicity in vitro is due to the reduced uptake of the metal by the cells possibly by direct binding to the -SH group of the amino acids.

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The use of immune checkpoint inhibitors, including nivolumab and pembrolizumab, in relapsed and refractory patients with lymphoma is proving highly successful. Value of physical and pharmacological tests in predicting intrinsic and extrinsic sick sinus syndrome. Desiccation of older leaves and the emergence of sporophores were observed from pathogen-inoculated seedlings, whereas a control seedling does not show any pathogenic symptoms. Suggestions and guidelines are given on areas in which people who are deaf and low functioning may need services beyond job placement. Chronic recurrent episodes of coronary spasm may lead to focal myocardial fibrosis.

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He was a bird-keeper who collected many species of exotic birds, including parrots. Clinical use of pentastarch in cardiac surgery without homologous blood transfusion. Influence of the intake and composition of elemental diets on bile acid metabolism and hepatic lipids in the rat.

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The results suggest the following: (1) 2,5-HD-induced protein cross-linking is mediated primarily by pyrrole-to-pyrrole bridging under physiologic conditions, and (2) glutathione and other low-molecular-mass thiols may inhibit the pyrrole dimerization reaction by two distinct pathways. The first wave of platelet aggregation, characteristic of ADP-dependent human tumor cell lines, was completely abolished but was replaced by a lag period prior to the onset of aggregation. Cellular susceptibility to apoptosis is determined by a variety of signals, of both extracellular and internal origin, including proliferative status.

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NRSN2 was more commonly down-regulated HCC tissues compared with adjacent tissues, and the expression pattern of NRSN2 was not only closely correlated with tumor size and TNM stage but also negatively correlated with patient prognosis. A hardware cochlear nonlinear preprocessing model with active feedback. The purpose of this case report is to describe the 25-year history of a man with a spinal cord injury who experienced severe musculoskeletal deterioration and hemicorporectomy. TAVI is associated with a high rate of silent cerebral ischemic lesions as evaluated by DW-MRI, with no differences between the TF and TA approaches.

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The wild-type mice, when given L-NAME for a week, showed a minimum alveolar concentration and RRED50 identical to that of untreated wild-type mice. Opioid analgesia is used more frequently in patients with chronic pain unresponsive to non-opioid therapy. Gelatin exhibits cross-linking upon storage at stress conditions. This first article will report on the in vitro evaluation of this system.

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13C-octanoic acid breath test in functional and organic disease: critical review of literature. The objectives were to use antibody reaction strength to differentiate patients who may have become RhD alloimmunized during pregnancy from those manifesting passive anti-D and to investigate which methods work best for this determination. Major complications (bile peritonitis, bleeding, and hemopneumothorax) occurred in 3 patients, which mainly arose in the earlier period of study. With this function, users can apply multiple services consecutively only by following links without any programming or manual copy-and-paste operations on Web browsers. The human stratum corneum was pretreated nonocclusively with formulations composed of laureth-3 oxyethylene ether (C12EO3), laureth-7 oxyethylene ether (C12EO7), and cholesterol sulfate (CSO4) prior to iontophoresis.

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Does Cerebral Water and Ion Imbalance After Intense Exercise of Short Duration Under Hypoxic Conditions Contribute to Occurrence of Acute Mountain Sickness? The aim of this study was to explore the occurrence of alexithymia and Early Maladaptive Schemas in a sample of 271 first visit chronic pain patients of six pain clinics.

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Recent studies with malignant B-cell lines show that, under certain experimental conditions, the extent and rate of surface clearing, uptake and intracellular transport are considerably higher in the case of CD19 than in CD10 and higher in less mature cells compared with more mature cells. Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a curative treatment for acute myeloblastic leukemia (AML). Maximum number of oocysts were found in mosquitoes which were fed on infected female mastomys on D8 and in male mastomys on D7 post-inoculation. Aggressive nutritional strategy in morbid obesity in clinical practice: Safety, feasibility, and effects on metabolic and haemodynamic risk factors.

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Correlations of headache diary parameters, quality of life and disability scales. We report the 3.0-Tesla MR imaging features of CAD in three patients and discuss the interest for this noninvasive imaging technique in such a setting. Molecular basis for a familial defect in phagocyte expression of IgG receptor I (CD64). In contrast, subcytotoxic concentrations of 10 microM MPTP resulted in lower, transient JNK activation in the presence of sustained ERK activity.

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The human ADAMTS (a disintegrin and metalloproteinase with thrombospondin-like motifs) family of 19 secreted, multidomain proteolytic enzymes is involved in a wide range of biological processes including ECM assembly and degradation, hemostasis, organogenesis and the regulation of angiogenesis. Blind docking of drug-sized compounds to proteins with up to a thousand residues. A radical nephrectomy typically includes early ligation of the renal vessels, excision of the kidney and perinephric tissue, a regional lymphatenectomy, and an adrenalectomy. If this is shown to be the case then a large randomised controlled trial is needed to provide an unbiased assessment of its utility in pre-discharge assessment. Discontinuous synthesis is inherently more complex, and fragmented intermediates create risks for disruptions of genome integrity.

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tRNAs are imported into mitochondria of Trypanosoma brucei independently of their genomic context and genetic origin. As the human immunodeficiency virus and sexually transmitted disease epidemics advance relentlessly, it is clear that an armamentarium of therapeutic and preventive methods will be essential to their containment. The long-term management following an hemicorporectomy (HCP) is not well documented in the scientific literature.

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The impact of family, peer, and school contexts on depressive symptoms in adolescents with spina bifida. Clinical evaluation of catheter-related fungemia and bacteremia.

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ERK1/2 has an essential role in B cell receptor- and CD40-induced signaling in an in vitro model of germinal center B cell selection. Recent evidence suggests that the transcription factor NF-kappaB is constitutively expressed in malignant gliomas and that its inhibition by drugs like Sulfasalazine may block the growth of astrocytic tumors in vitro and in experimental models of malignant gliomas.

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Azide and hydroxylamine release nitric oxide (NO) enzymatically in biological conditions. The recent exciting advances in our understanding of the regulation of the energy sensor AMP-activated protein kinase (AMPK), together with renewed appreciation of its importance in maintaining cellular function, brought together leading scientists at a recent FASEB-sponsored meeting in September 2014.

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Therefore, minimising the impact of adverse events (AEs) on patient quality of life is important to enable patients to achieve optimal exposure to sunitinib and maximum clinical benefit. Further, we show that other disulfide-containing proteins, namely single-chain Fv and heterodimeric F(AB) antibody fragments, are export-competent only in strains having an oxidizing cytoplasm. The major molecular constituents of basement membranes are collagen IV, laminin-entactin/nidogen complexes, and proteoglycans. To investigate the changes in cerebral blood flow in patients with maxillary defect treated with prosthesis insertion. Isolated pulmonary interlobular arteries (PA) and veins (PV) were obtained from a local slaughterhouse.

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Sanasol was found to be ineffective in experimental renal failure. High efficiency of BRCA1 knockout using rAAV-mediated gene targeting: developing a pig model for breast cancer. Seryl-tRNA synthetase from Escherichia coli: functional evidence for cross-dimer tRNA binding during aminoacylation.

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The evolution of Lyme borreliosis, including infection and the development of arthritis and carditis, was similar in transgenic and nontransgenic littermates suggesting that an OspA or B immune response is not singularly involved in either the genesis or regression of Lyme disease in C3H or B6 mice. On reviewing the English literature, 5 AAV patients with coexisting VTE and PH have been reported. Lungs from animals exposed intranasally contained only 747, 62 and 1424 spores per gm of tissue respectively.

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Study of plasma corticotropin and cortisol activities in children during acute articular rheumatism and infectious diseases before institution of treatment The apparent stability constants of the alpha- and beta-cyclodextrin complexes are 10.29 M-1 and 148.88 M-1, respectively. Islet purification by magnetic separation has shown early promise. This increased interest of scientists is to a great part due to the development and use of real-time PCR techniques to identify and quantify airborne microorganisms. The present study evaluated the clinical significance of long-term psychoanalytic treatment in four groups of about 60 patients in different phases of treatment (before, during, after, follow-up) with normative comparisons on four symptom questionnaires (SCL-90, BDI-II, STAI, IIP-64) and two personality assessment instruments (MMPI-2, Rorschach-CS).

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The presence, activity, and distribution of NOS were described in two regions of the human prostate. The effects of morphine, hypoxaemia or hypercapnia on gastric acid secretion, gastric mucus synthesis and the gastric mucosa were studied in conscious rats with pyloric occlusion. Although the secondary structure arrangement and the binding mode of catalytic and structural zinc ions in PFDH are similar to those of typical ADHs, a number of loop structures that differ between PFDH and ADHs in their lengths and conformations are observed. Analysis unit: positivity of the test and presence or absence of illness confirmed by histologic analysis of the appendix obtained through laparotomy. The environment, including diet and hygiene, may be among the factors influencing these differences.

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Decreasing effect of propranolol on hypertension induced by potassium cyanide in dogs Tumors of the stomach and the right side abdominal wall were diagnosed by FDG/PET-CT.

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Endothelium-dependent and endothelium-independent skin vasoreactivity in the elderly. Bcr-Abl is one of the most potent antiapoptotic molecules and is the tyrosine-kinase implicated in Philadelphia (Ph) chromosome-positive leukemia. Assays combining radiation with gemcitabine in different dose and time schedules demonstrated no radiosensitizing effect in TCC cells. Ursodeoxycholic (UDC) and dehydrocholic (DHC) acids were tested as potential enhancers, alone or in combination with different aminoacids.

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Neonatal cholestasis syndrome with an intra or extrahepatic origin has been associated to viral infections. Survival rate of extremely low birthweight infants and its effect on the amendment of the Eugenic Protection Act in Japan.

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Fibrocyte CXCR4 regulation as a therapeutic target in pulmonary fibrosis. Changes in the expression of GABA(A) receptor subunit mRNAs in treated cultures suggest that neuronal activity can regulate their regional expression in vitro. The enzyme also occurred in human saliva, milk, cerebrospinal fluid, and synovial liquid. Household willingness to pay for azithromycin treatment for trachoma control in the United Republic of Tanzania.

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Moreover, the ultrasonic nebulizer does not require sample preconcentration. Blood pressure (BP) and heart rate (HR) have been monitored over a 24-hour period to detect whether circulating VIP in heart transplanted patients is influenced by pharmacologically-induced interactions. Bovine platelet factor 4 shares sequence similarities proportionately with both human platelet factor 4 and beta-thromboglobulin. Increased levels of cdk4 and cyclin D1 proteins were found in the colonic epithelium of progastrin-overexpressing mice relative to wild-type animals after gamma-radiation.

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Serotonin metabolism in the framework of aggression and violence Levels of catecholamines and activity of the renin-aldosterone system in women with hypertension in the period before and after menopause Markedly higher levels of WBC and Hb, lower level of blood C4 in HSPN compared with IgAN cases were observed among patients with fibrogen deposition. Binding and the effect of the red kidney bean lectin, phytohaemagglutinin, in the gastrointestinal tract of suckling rats.

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Studies have shown the combination of either focal irradiation and hemibody irradiation or focal irradiation and the injection of strontium (89) prolongs the pain-free duration of the patients. Determination of trace lithium in human urine by electrothermal atomic absorption spectrometry using nitric acid as a chemical modifier to eliminate the interference of chloride. The brain activity of adolescents during an endogenous cognitive control task is associated to the level of anxiety experienced by their mother during pregnancy.

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The rhythm has two phase markers, namely the time of the dumocycline tetracycline hcl 500 evening NAT rise and that of the morning decline. Here, we review the application of computational methods toward several clinically important NRs (with special emphasis on PXR) and discuss their use for screening and predicting the toxic side effects of xenobiotics. Delineation of a carboxy-terminal epitope with peptide antibodies. This article summarizes a symposium held at the 2002 Annual Meeting of the Research Society on Alcoholism in San Francisco, CA, and was prepared on behalf of the symposium participants by the symposium co-organizers/co-chairs. Bone turnover in overt and subclinical hyperthyroidism due to autonomous thyroid adenoma.

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In the present study an adenovirus vector expressing p16 or p21 genes in human glioma cell lines was used to examine cell cycle regulation and cell death induced levofloxacin antibiotic coverage for atypical pneumonia by staurosporine. Images reconstructed with the proposed model contain correlated noise structures which are difficult to characterize with accepted NEMA noise metrics.

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Viral DNA sequences were detected in 53 samples, a fifth of which had been previously serotyped as HCMV negative. A newly developed assay system which uses actinomycin D (Act D) pretreated Wehi 164 target cells allows for the measurement of human monocyte cytotoxicity in a 7-h 51Cr release assay. The esophageal balloon pull-through technique for esophageal dilation duloren online games in patients with EoE appears to be safe and effective.

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Two novel and eight known triterpenoids were isolated from alcoholic extract of the whole plant of Pyrethrum tatsienense. Evidence-based nursing care management for the pregnant woman with an ostomy. In this analysis, the influence varied between the different nexe cezar cena vs lesnar medical specialties. Integrins beta1 and beta3 gene expression and protein production were low in sham-operated hearts. Effect of nonadditive repulsive intermolecular interactions on the light scattering of concentrated protein-osmolyte mixtures.

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Giant aortic root aneurysm in Marfan syndrome: a rare complication in early childhood. Gonadotropins and ovarian carcinogenesis: a new era of basic research and its clinical implications. These results indicate that pantoprazole dosage before or after foods the age-related susceptibility to AOM differs depending on whether administration of the carcinogen is based on weight or total dose.

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