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Topiramate
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Topiramate

Topiramate is the brand name used in the United States, Canada, the United Kingdom, Australia, and some other countries for the seizure medicine Topiramate (toh-PEER-ah-mate). Topiramate is not available in generic (non-brand) form in the United States. There is also an extended release formulation targeted for mid-2013. Topiramate is marketed in the United States by Ortho-McNeil Pharmaceuticals. The name or appearance may differ in other countries. The dose (measured in milligrams, abbreviated "mg") will usually be the same.

Other names for this medication:
Topiramate, Topamax, Epitomax, Letop, Neutop, Piramax, Talopam, Topamac, Topictal, Topigen, Topilex, Topimax, Topina, Topiramato, Topirol, Toplep,

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Topiramate is used alone or with other medications to prevent and control seizures (epilepsy). This medication is also used to prevent migraine headaches and decrease how often you get them. Topiramate will not treat a migraine headache once it occurs. If you get a migraine headache, treat it as directed by your doctor (such as by taking pain medication, lying down in a dark room). Topiramate is known as an anticonvulsant or antiepileptic drug.

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At present the recommendations for management are limited because of the paucity of definitive clinical trials. Modulation of foregut synaptic activity controls resorption of molting fluid during larval molts of the moth Manduca sexta. At screening, individuals completed two questionnaires to measure self-esteem, the Rosenberg self-esteem scale and the Janis and Field Social Adequacy scale.

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Matrix metalloproteinase-9 activity in the cerebrospinal fluid and serum of dogs with acute spinal cord trauma from intervertebral disk disease. Cyclic AMP-mobilizing agents and glucocorticoids modulate human smooth muscle cell migration. CD, IR, and CD/IR measurements were correlated to the fraction of the motif to be predicted, determined from X-ray measurements. It sustained at this higher level on the 15th and 42th days, and the similar changes were observed in RV as well.

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The ubiquitous and dominant rapid cytosolic isozyme hCA II was also inhibited with KIs ranging from 3.5 to 45.4 nM. The data from this study indicate that measurement of serum soluble c-kit concentration is a useful indicator of severe acute GVHD. The good results obtained with the use of the apparatus warrant its wider application.

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The active receptor protein is derived from a 600-kDa precursor, encoded by a 15-kb mRNA, cloned and sequenced in human, mouse, and chicken. Axillary and tympanic membrane temperature measurements are unreliable early after cardiopulmonary bypass. Preservation of neurological functions by nitric oxide synthase inhibitors following hemorrhagic shock.

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Factors inducing migration are reviewed, as well as the therapeutic potential of these factors in regulating the immune response. Computed tomography (CT) imaging of the kidney, ureter, and bladder permit accurate and prompt diagnosis or exclusion of traumatic injuries, without the need to move the patient to the fluoroscopy suite. We therefore tested the hypothesis that all these processes depend on the presence of VGLUT3 by comparing the Glu-dependent component of DSE, DPI, and DISC in nearly mature (2- to 3-wk-old) wild-type and VGLUT3 knockout mice. We studied in vivo activated T lymphocytes that infiltrate atherosclerotic plaques of Helicobacter pylori-infected patients with or without anti-Chlamydia pneumoniae antibodies.

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Female sex hormone, estradiol, antagonizes the immunosuppressive activity of cyclosporine in rat organ transplantation. The MMCs of the spleen and kidney trap carbon material 48 hours after injection of Indian ink. Decidual LPS-induced NO production was abrogated either by co-incubation with CB1 (AM251) or CB2 (SR144528) antagonists which suggests that both receptors could be mediating this effect. The placebo inhibitory effect on FHM by a blank goggle frame indicated that acquisition of learning affected the frequency of FHMs per se. This study aimed to compare the antibiotic susceptibilities, serotypes and genotypes of pneumococci causing pneumonia or acute exacerbations of chronic obstructive pulmonary disease (AECOPD) in patients with COPD.

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In the connective tissue capsule of the testis also small calcitonin gene-related peptide- and metenkephalin-containing nerve fibres were seen. Exposure to ionizing radiation from medical diagnostic imaging procedures may occur frequently among children. We identified various phases of engagement in the process of a long-term dietary intervention among middle-aged women. A retrospective, nonrandomized, single-center clinical study was designed to evaluate the outcomes of corneal collagen crosslinking (CXL) for progressive keratoconus in Iranian patients 12 months after CXL.

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To assess the reliability of the landmarks for the rotationally neutral alignment of the tibial component in total knee arthroplasty for Japanese patients, the rotational position of the medial (1/3) of the tibial tuberosity relative to the femoral epicondylar line (Angle TT) and that relative to the center of the ankle (Angle TT-AA) were measured in 24 knees with medial femorotibial osteoarthritis and in 28 normal knees by computed tomography. Results of the re-examination of the disabled in the town of Osh, Kirgh.

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Moreover, IFN-gamma-triggered apoptosis is independent of the cellular phenotype (schwannian or neuronal) and appears to be mutually exclusive with respect to differentiation at the single cell level. LMV, as with other nucleoside analogues including Famciclovir (FCV), suppresses the replication of hepatitis B virus (HBV) by targeting the viral polymerase.

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Tumor necrosis factor-alpha induces apoptosis in rat brown adipocytes. However, for many of the stent-grafts tested, the safety margin was small. Recently, functional replacement of one channel gene with another in mice and flies has revealed that cellular health depends not simply on gap junction communication but also requires the correct type of intercellular channel subunit. Effect of 5-diazouracil on the catabolism of circulating pyrimidines in rat liver and kidneys.

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These results were used in the calculations of the free CS concentrations in the donor chamber of the transport experiments. Changes in macronutrient, micronutrient, and food group intakes throughout the menstrual cycle in healthy, premenopausal women. Staff reduction during holiday periods in units that care for acute surgical patients may adversely influence postoperative outcome.

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Substituting tenofovir for stavudine in resource-limited settings: there are challenges ahead. Chest computed tomography (CT) showed a 10.0 x 6.6 cm mass arising from the left chest wall.

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A single oral dose of levamisole hydrochloride given at the rate of 12 mg/kg was believed responsible for bradycardia, tachypnea, hypothermia, cerebrocortical depression, and diarrhea in a dog. Therefore, we xenografted subcutaneously into nude mice seven human colonic tumours (from stages B1 to D) that showed chromosome instability and transplanted them sequentially for up to 14 passages.

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The development of minimally invasive surgical techniques has introduced a new era in surgical management. This work improves our understanding of the local social dynamics driving migratory band formation, maintenance and movement at the population level. In conclusion, piezosurgery is a promising technical modality for different aspects of bone surgery with a rapidly increasing number of indications throughout the whole field of surgery.

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Sub-Saharan Africa is the most severely affected, accounting for more than 80 percent of those orphaned as a result of AIDS. However, studies comparing allograft-related outcomes between these anti-CMV approaches are lacking. This is a characteristic finding of which ocular pathologists and corneal surgeons should be aware.

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Following stimulation with MHV-A59, it was shown by electrophoretic mobility shift assay that HNF4alpha binds the HNF4 cis-element in the fgl2 promoter. Immunological changes in women with infertility of an inflammatory origin and their correction This work successfully set exposure guidelines to identify a biologically active dose in early clinical trials. Studies of tissue respiration and oxidative phosphorylation of homogenates in the liver of white rats indicated that the 3-day hypokinesia is associated with a decreased rate of endogenic respiration and an increased amythal-resistant respiration.

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Regulation of the central glycolytic genes in Bacillus subtilis: binding of the repressor CggR to its single DNA target sequence is modulated by fructose-1,6-bisphosphate. This review presents intriguing evidence that part of the anticancer properties attributed to several bioactive food components, encompassing both essential nutrients and non-essential components, may relate to DNA methylation patterns. In the case of hilar bile duct cancer, which may extend into the dorsal ducts (especially the right lateral duct), partial or total caudate lobectomy is often necessary for complete extirpation of the tumor.

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Use of radioactive liquid culture media (Bactec) or not, has shortened the time required for obtaining the result, but it remains too long and, so far, polymerase chain reaction has not answered the challenge. The techniques described below can make large numbers of different peptides simultaneously with varying degrees of mechanization, ranging from the wholly manual methods, to those involving complete mechanization of the whole synthesis process.

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The injection of the spleen mononuclear (SpM) cells, obtained from rats rendered unresponsive to autoantigen of rat male accessory glands (RAG) by pretreatment with low doses of purified fraction of RAG (containing the autoantigen), into normal syngeneic recipients markedly prevented the development of delayed type hypersensitivity (DTH) reaction to the autoantigen (suppression of the induction) (p less than 0.001). Controlling the electronic structure of carbon nanotubes (CNTs) is of great importance to various CNT based applications. However, relatively abundant alternatively spliced CAD transcripts with fusion of exon 2 to exon 6 or 7, in which the corresponding domain directing CAD interaction with ICAD was preserved, were found only in poorly differentiated Mahlavu and SK-Hep1 cells.

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Neurogenic potential of human umbilical cord blood: neural-like stem cells depend on previous long-term culture conditions. The solutions are provided through interdisciplinary and holistic reasoning. Phase II trial of pegylated-liposomal doxorubicin (Doxil) in sarcoma. Production of trichothecene mycotoxins by Australian Fusarium species. To explore the therapeutic effect of Hejie Decoction (HJD) in treating chronic hepatitis B and its relationship with T-cell receptor V beta 7 (TCRV beta 7) gene expression.

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Skin metastases from urothelial carcinoma of the bladder are uncommon, and there are few cases reported in literature. Impairments in spatial working memory are seen only after longer durations of CORT administration. Complexes were detected using AlphaScreen technology or time-resolved FRET. The bone marrow is a primary and sensitive target for this drug, which causes a selective loss of stem cells in S phase.

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It has become apparent that expression of a subset of TLRs (TLR1, TLR2, TLR3, TLR5, and TLR7) is induced by Type I interferons (IFN). The level of inducible NO synthase mRNA in LPS/IFN gamma-activated RPE cells is markedly reduced by FGF-1 or FGF-2 treatment. Here, we review recent investigations on how baculoviruses interact with insect cells and insect hosts. The GFP diffusion coefficient remains constant regardless of the type of coexpresseed protein and whether or not the coexpressed protein was induced. Although the most common clinical manifestation is eye involvement as ligneous conjunctivitis, extra-ocular lesions affecting other mucosal surfaces indicates a systemic disease.

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Estimation of VLDL, IDL, LDL, HDL2, apoA-I, and apoB from the Friedewald inputs--apoB and IDL, but not LDL, are associated with mortality in type 1 diabetes. Five Challenges Facing the US Physician Workforce (And What to Do About Them). The present study is the first to examine the modulation of retinal kynurenic acid (KYNA) content in response to N-methyl-D-aspartate (NMDA)-induced cell death in adult rat retinal ganglion cells (RGC). Fusing Functional MRI and Diffusion Tensor Imaging Measures of Brain Function and Structure to Predict Working Memory and Processing Speed Performance among Inter-episode Bipolar Patients. We found increased levels of aldosterone and ambulatory blood pressure (BP) in G carriers only for rs5522.

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Research interests in the field of behavioral, psychosocial, and policy cancer research. Plasma PAI-1 levels are more strongly related to liver steatosis than to adipose tissue accumulation. But there was a several times difference between the youngest and the oldest animals in the level of contamination of these tissues was. Glycoregulation is not altered by short-term administration of diltiazem in nondiabetic humans.

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Emerging evidence suggests the same cues control dendrite development, but it is not understood how they differentially instruct axons and dendrites. Serologic surveillance of influenza during the epidemic season 1990/91 in Poland Excitation-contraction coupling in rat myocardium: alterations with long term ethanol consumption. Computationally, a downhill simplex optimization method is used to minimize the error function with respect to the fractional MUs. Labyrinthine pressures and breaking point of the endolymphatic space.

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Instrumental diagnostic investigations (ultrasonography and CT scan) revealed an adrenal mass of uncertain interpretation which was surgically removed and histologically diagnosed as a cavernous haemangioma. Twice weekly IFA supplementation is comparable to daily IFA in terms of beneficial effects on physical work capacity in young girls. Colour Doppler ultrasound and angiogram were performed to confirm diagnosis.

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The arteries were perfused by both high pressure (160 mmHg) and normal pressure (80 mmHg) for 6 hours. Sections discuss the role of epidemiology, the spread of HIV through infected needles and syringes, AIDS and HIV in Maharashtra, and the economics of AIDS. Studies in deuterated buffer show that solvent-derived deuterium is quantitatively incorporated into the C-2 position of the product during catalysis, but it is not incorporated into the remaining pool of substrate. Nevertheless, the diet conserved the high intake of monounsaturated and polyunsaturated fatty acids which is characteristic of traditional Mediterranean food.

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Very recent data obtained with Rotarix support the suggestion that factors other than neutralizing antibody can play important roles in protection against rotavirus disease after live rotavirus immunization. This can be due to problems in financial resource management especially in asset combining. EPF values were more scattered and less reproductible with Assess, but the difference was not significant. morning hours) as well as during the total 24-h sampling period. Evidence for an unusual distribution of chlorphentermine in vivo.

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PKC activity was increased in dose-dependent manner by CCK8(10(-11)-10(-6) mol/L). In all groups, total leukocytes, neutrophils, lymphocytes, and monocytes increased at end-exercise, but returned to baseline by 30-min postexercise, including neutrophils, previously reported to remain elevated for at least some exercise formats. If you use a paper system, ensure that all final printed results are filed in the paper record. Non-small cell lung cancer with chest wall invasion: evolution of surgical treatment and prognosis in the last 3 decades. Nitrogen, sulfur and carbon fluxes in the terrestrial subsurface are determined by the intersecting activities of microbial community members, yet the organisms responsible are largely unknown.

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Some molluscan, annelid, and echinoderm species can probably serve as objects for isolation and detailed study of the fucoidan-hydrolyzing enzymes. Bilateral 6-hydroxydopamine lesions of the locus coeruleus projection to the forebrain were found to aggravate neuronal necrosis in the neocortex following 60 min of flurothyl-induced status epilepticus. Regulation of endoplasmic reticulum turnover by selective autophagy. Numerous Treponema hyodysenteriae were present both on the mucosal surface and in the deep crypts of the cecum of young broiler chicks 7 and 14 days after inoculation with the treponemes. Evaluation of intervention strategies to address these vulnerability factors is a priority.

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Fibronectin binding sites of collagen IV were mapped to unfolded structures of the major triple-helical domain and show a similar specificity to fibronectin-binding sites of collagen I. The role of surgery in the management of mesothelioma has largely been confined to obtaining a tissue diagnosis or to effect symptom control by pleurodesis. Hemagglutination and proteoglycan binding by the Lyme disease spirochete, Borrelia burgdorferi. A great deal of work has gone into the study of the leptospires and leptospirosis, and the present paper reviews these works, concentrating on serovar lai (the major serovar in China) and pulmonary diffuse hemorrhage (PDH), a traumatic consequence of leptospirosis.

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MKT1 is required for maintenance of K2 above 30 degrees C in strains with the L-A-HN fenactol diclofenac tablets 75mg variant of the L-A double-stranded RNA virus of Saccharomyces cerevisiae. The memory for a fine motor task appears to be sensitive to post training stage 2 sleep loss.

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Clinicians see many more nonagenarian patients now and there is a need for epidemiological data relating to this group. The Inositol 1,4,5-triphosphate kinase1 gene affects olfactory reception in diazepam withdrawal effects Drosophila melanogaster. The effect of VVI pacing on P-wave dispersion in patients with dual-chamber pacemakers. Numerous fusion events indicated that HIV-1 infection of B lymphocytes could spread to T lymphocytes following HIV-1-mediated fusion of these two cell types.

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The wear model was based on the classical Archard-Lancaster equation in common with all other studies reported in the literature. In addition, we found a dose-dependent reduced activation of p38 and STAT3 in axitinib-exposed DCs, whereas the expression was not affected. Neurotoxicogenomic investigations to stomach acid reflux drugs pantoprazole assess mechanisms of action of the munitions constituents RDX and 2,6-DNT in Northern bobwhite (Colinus virginianus).

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However, the analysis of the various dexyclav forte adalah center bracket-archwire combinations showed that Damon SL II brackets generated significantly lower friction than the other brackets when tested with round wires and significantly higher friction than Time Plus when tested with rectangular archwires. In 20 patients there was evidence of root compression by disc tissue. Simian virus 5 (SV5) is a member of the paramyxovirus family, which includes emerging viruses such as Hendra virus and Nipah virus as well as many important human and animal pathogens that have been known for years.

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The distribution apo bromocriptine pregnancy category of the number and volume of liver metastases in both lobes of the liver was investigated. The filling characteristics were studied within this operating space.

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Furthermore, cardiac expressions of endothelial nitric oxide synthase, superoxide dismutase 2, and B-cell lymphoma 2 were significantly enhanced, but tumor necrosis factor alpha, NFKB1 motifene dual 75 mg hinta (p50 and its precursor, p105), neurotrophin-3, Bcl-2-associated X protein, calpain, caspase 12, caspase 9, and caspase 3 were significantly suppressed in DOX-treated mice under oral treatment with the herbal formula B307. Investigation of the structure of trimeric and monomeric photosystem I reaction centre complexes.

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Patients with hematologic malignancies can survive severe, invasive aspergillosis during prolonged periods of neutropenia with a combination of chlorpromazine equine dosage oxytetracycline antifungal and growth factor therapies, donor granulocyte infusions, and surgical debridement. Early dysphagia after placement of a self-expanding esophageal stent: severe esophagitis mimicking luminal occlusion.

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Quality of Life after Diet or Exercise-Induced Weight Loss in Overweight to Obese Postmenopausal Women: The SHAPE-2 Randomised Controlled Trial. We improved parts of the bioPerl library to allow parsing of large data files, and we embedded these scripts in a user friendly interface (OS independent) for easy use. This was a secondary analysis from patients cefdinir dosage uti excluded from a previous retrospective study regarding uncomplicated UTIs. Specifically, we review novel developments in our understanding of CAD pathophysiology, diagnostic applications, prognostic studies, clinical trials, and clinical guidelines. We redefined and updated a cohort of male workers employed in industrial facilities where EO was produced or used.

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Relationship between white spot syndrome virus and indicators of quality in Penaeus monodon postlarvae in Karnataka, India. The majority of labelled neurons resembled Dogiel type I morphology. Qualitatively, conceptual categories of impact were created using betacin tablets best the Constant Comparative Method. To present radiation therapy as a viable treatment option to amputation for surgically unresectable subungual squamous cell cancer.

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We advocate that a vaccination programme be alfuzosin hcl 10 mg ranbaxy accompanied by education about hydatid disease, and anthelmintic treatment of dogs in late autumn and early spring. Functional endoscopic sinus surgery (FESS) is the standard of care for the surgical management of sinonasal inflammatory disease. The cytokines were measured before operation and on postoperative days 1, 3, 7, 10, and 16.

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ATM depletion in metastatic cancer cells reduced cell migration and invasion. A rank-order (dose-dependent) increase in p75(NTR) protein expression was spironolactone acne photos associated with a decrease in cell proliferation. Inter-site variability accounted for only 5.4 percent of the total variability noted in these observations. In warm years the percentages of primitive anthocyanins (delphinidin 3-O-glucoside and petunidin 3-O-glucoside) were slightly lower than in a relatively cool year. PAI-1 inhibitors appear to exhibit potent effects on the prevention of adverse tissue remodeling.